NDLI: MHC-inspired Antibody Clone Algorithm for Multimodal Function Optimization

Content Provider	IEEE Xplore Digital Library
Author	Yu Zhang Lihua Wu Feng Xia
Copyright Year	2009
Abstract	Intelligent optimization algorithms based on biological mechanisms have better performance than traditional ones in solving complex multimodal function optimization problems. Most of those intelligent algorithms, however, have the problems of degeneration and vibration, which will lead to poor global optimization and low convergence speed. Inspired by the features of MHC (Major Histocompatibility Complex) in the biological immune system, a novel MHC-inspired antibody clone algorithm (MOAMHC) was proposed to solve the above problems. This algorithm preserves elitist antibody genes through the MHC strings that emulate the MHC haplotype in order to improve its local search capability. It enhances the antibody population diversity by gene mutation that mimics the MHC polymorphism and polygenism to improve its global search capability. The convergence of MOAMHC is theoretically proved. The experiments of MOAMHC on some multimodal mathematical functions and a practical malicious code detector optimization problem are carried out. The proposed algorithm shows competitive results with improved diversity and convergence. It provides new opportunities for solving previously intractable function optimization problems.
Starting Page	56
Ending Page	63
File Size	489618
Page Count	8
File Format	PDF
ISBN	9780769539034
DOI	10.1109/SERA.2009.36
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-12-02
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cloning Immune system Educational institutions Information science Software algorithms Genetic mutations Convergence Optimization methods Software engineering Conference management
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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