NDLI: A new automatic segmentation method for lung tumor based on SUV threshold on $^{18}F-FDG$ PET images

Content Provider	IEEE Xplore Digital Library
Author	Xin Ming Yuanming Feng Yu Guo Chunmei Yang
Copyright Year	2012
Description	Author affiliation: Dept. of Biomedical Engineering, Tianjin University, Tianjin Key Lab of BME Measurement Technology, China (Xin Ming; Yuanming Feng; Yu Guo; Chunmei Yang)
Abstract	Heart metabolizes more glucose and “light up” more brightly on PET lung images than other healthy or normal tissues and organs because of its constant pumping of blood and accumulation of radiotracer concentration. It affects the results of lung tumor detection and segmentation using the thresholding methods, which is the most used methodcurrently. Standardized uptake value (SUV) on $^{18}F-FDG$ PET images isan important indicator to differentiate malignant from benign tumors, and has been applied in tumor volume segmentation. However, some methods based on SUV have been shown unable to distinguish regions between tumor and heart. In this paper, we present a novel segmentation method based on SUV to extract the tumor alone from the background ofhealthy tissues and image noise. Firstly we use SUV to enhance the images and then apply an iterative thresholding method to get a coarse result. Secondly we label the fragmented parts and fuse them with the SUV distribution image, and then calculate the SUV for each part. Finally we use the maximum of SUV to locate the tumor region. The proposed method is compared with current segmentation methods on PET images. The results show that the new method is able to detect tumors in the background of heart effectively, and can potentially be used as a toolof automatic segmenting tumor from $^{18}F-FDG$ PET images.
Starting Page	5
Ending Page	8
File Size	1175769
Page Count	4
File Format	PDF
ISBN	9781457717581
ISSN	19449429
e-ISBN	9781457717598
DOI	10.1109/VECIMS.2012.6273223
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-07-02
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Tumors Image segmentation Positron emission tomography Lungs Heart Biochemistry Cancer Thresholding SUV PET images
Content Type	Text
Resource Type	Article

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