NDLI: Multiscale, multimodal, and multidimensional microscopy of cardiac development

Content Provider	IEEE Xplore Digital Library
Author	Liebling, M. Bhat, S. Jungho Ohn
Copyright Year	2010
Description	Author affiliation: University of California Santa Barbara, Electrical and Computer Engineering Department, Santa Barbara, CA 93106-9560 (Liebling, M.; Bhat, S.; Jungho Ohn)
Abstract	In vivo fluorescence imaging of the embryonic zebrafish heart as it develops and gains function has recently become possible thanks to several breakthroughs in fast microscopy. However, because of the motion of the fast beating heart, volumetric, long term, continuous, and simultaneous characterization of subtle changes in heart morphology at the organ, tissue and cellular level, changes in heart function, or changes in local gene expression all remain major challenges. We have developed tools that aim at addressing the problem of capturing and integrating multi-modal data at different temporal and spatial scales to build a multi-dimensional model of the beating and developing heart. This paper gives an overview of techniques we developed and integrated to follow heart development, spatiotemporally confined hemodynamics, and gene expression. These tools permit quantitative characterization and will allow studying the interactions between genetic and epigenetic factors that affect cardiac development.
Starting Page	227
Ending Page	230
File Size	64342
Page Count	4
File Format	PDF
ISBN	9781424489329
ISSN	15206130
e-ISBN	9781424489336
e-ISBN	9781424489343
DOI	10.1109/SIPS.2010.5624794
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-06
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Heart Microscopy Gene expression Optical imaging Embryo Valves zebrafish registration optical flow wavelets
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

In Vivo Continuous imaging of Vertebrate Cardiac Valves for Congenital Heart Disease Study and Medical Drug Screening Using Third Harmonic Generation Microscopy

Cardiac tissue and erythrocyte separation in bright-field microscopy images of the embryonic zebrafish heart for motion estimation

In vivo, high-throughput imaging for functional characterization of the embryonic zebrafish heart

Automated heart rate estimation in fish embryo

Estimation of divergence-free 3D cardiac blood flow in a zebrafish larva using multi-view microscopy

Noninvasive multi-modality nonlinear imaging of heart development using transgenic zebrafish lines tagged with Hc-red fluorescence proteins

A field approach to spatial gene expression in zebrafish heart development.

Effects of simulated-microgravity on development and p53 gene expression of zebrafish embryos

Simulating gene expression patterns of (2003).

Multiscale, multimodal, and multidimensional microscopy of cardiac development

Similar Documents

In Vivo Continuous imaging of Vertebrate Cardiac Valves for Congenital Heart Disease Study and Medical Drug Screening Using Third Harmonic Generation Microscopy

Cardiac tissue and erythrocyte separation in bright-field microscopy images of the embryonic zebrafish heart for motion estimation

In vivo, high-throughput imaging for functional characterization of the embryonic zebrafish heart

Automated heart rate estimation in fish embryo

Estimation of divergence-free 3D cardiac blood flow in a zebrafish larva using multi-view microscopy

Noninvasive multi-modality nonlinear imaging of heart development using transgenic zebrafish lines tagged with Hc-red fluorescence proteins

A field approach to spatial gene expression in zebrafish heart development.

Effects of simulated-microgravity on development and p53 gene expression of zebrafish embryos

Simulating gene expression patterns of (2003).

Multiscale, multimodal, and multidimensional microscopy of cardiac development