NDLI: On-chip cell manipulation by magnetically modified soft microactuators

Content Provider	IEEE Xplore Digital Library
Author	Yamanishi, Y. Sakuma, S. Arai, F.
Copyright Year	2008
Description	Author affiliation: Dept. of Bioeng. & Robot., Tohoku Univ., Sendai (Yamanishi, Y.)
Abstract	We have developed magnetically modified polymeric soft microactuators in microchip as replacement of conventional manual cell manipulations such as pipetting and centrifugation. In the past papers in Yamanishi, Y., et al, (2007) we have reported novel magnetically driven polymeric microtools for non-intrusive and no contamination experiments on a chip. The main features of them were 1. fabrication of any shape, 2. soft (harmless to cellls) 3. no stiction and 4. mass production at low cost enabling disposability. For the current research, we have demonstrated manipulation of oocyte with produced novel soft microactuators. These magnetic microtools provide a number of functions such as microvalve and microrotor. The potential impact of this technology includes sample preparations, selection and separation, loading and immobilization, genetic operation, tracking, mixing and reaction techniques into portable microfluidic labs-on-a-chip, culture systems.
Starting Page	899
Ending Page	904
File Size	1594729
Page Count	6
File Format	PDF
ISBN	9781424416462
ISSN	10504729
DOI	10.1109/ROBOT.2008.4543319
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-05-19
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Soft magnetic materials Microactuators Magnetic separation Polymers Contamination Fabrication Shape Mass production Costs Micromagnetics
Content Type	Text
Resource Type	Article
Subject	Artificial Intelligence Control and Systems Engineering Electrical and Electronic Engineering Software

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