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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Li Yuan Mi Basu, M. Fritton, S. Cowin, S. |
| Copyright Year | 2002 |
| Description | Author affiliation: Dept. of Electr. Eng., City Univ. of New York, NY, USA (Li Yuan Mi; Basu, M.) |
| Abstract | The objective of computational connected cellular network (CCCN) is to model a network of bone cells and study the mechanical loading induced signal communication pattern among them. Our previous study (2000, 2001) has shown that a backpropagation (BP) neural network model can be used to capture the functional relation between the mechanical loading and the amount of bone formation. To emulate the cell-to-cell communication pattern in bone matrix, a new computational connected cellular network (CCCN) learning system has been developed with a structure that closely mimics the actual biological structure of cell-connections in a bone. An error-correcting learning algorithm is proposed for CCCN based on a two-dimensional extension of the backpropagation algorithm. The CCCN is divided into numerous BP networks, whose architecture changes with weights and cell-state updating cycles. The conventional BP learning algorithm can be applied to each BP network. It is convergent because of the constraints enforced by the characteristics of a real bone cell. Application of the CCCN to an animal bone adaptation experiment produces interesting cell communication patterns. |
| Sponsorship | Asia-Pacific Neural Network Assembly Singapore Neuroscience Assoc. SEAL & FSKD Conference Steering Committees IEEE Neural Networks Soc. Int. Neural Network Soc. Eur. Neural Network Soc. SPIE |
| Starting Page | 503 |
| Ending Page | 506 |
| File Size | 311945 |
| Page Count | 4 |
| File Format | |
| ISBN | 9810475241 |
| DOI | 10.1109/ICONIP.2002.1202221 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2002-11-18 |
| Publisher Place | Singapore |
| Access Restriction | Subscribed |
| Rights Holder | Nanyang Technological University |
| Subject Keyword | Computer networks Land mobile radio cellular systems Bones Biomedical computing Biomedical engineering Neural networks Learning systems Animal structures Cells (biology) Mechanical engineering |
| Content Type | Text |
| Resource Type | Article |
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