NDLI: Temporal observation of apoptosis in tumor tissues via electrochemical treatment (EchT)

Content Provider	IEEE Xplore Digital Library
Author	Hong Bae Kim Sungbo Sim Saeyoung Ahn
Copyright Year	2004
Description	Author affiliation: Solco Biomed. Inst., Seoul Nat. Univ., South Korea (Hong Bae Kim)
Abstract	Summary form only given. Growth, arrest and suicide (apoptosis) of cells are all legitimate responses associated with DNA damage, although the choice of fate in each instance depends upon the cell type, location, environment, and extent of its damage. Apoptosis is a fundamental mode of cell death, which performs a regulatory function during normal development, in tissue homeostasis, and in some disease processes. Apoptosis may be the prudent option in damaged cells that retain substantial replicative potential and therefore constitute a neoplastic risk. To induce apoptosis, various means are chosen among the X-ray, UV-radiation, anti-tumor drugs, and direct current, the last of which is the choice of tool for this paper for study of tumor tissues such as tumor regression and its necrosis. The modality of direct current in apoptosis has gained vast interest lately, Temporal variation of apoptosis by means of direct current will provide a clue to the series of immune reaction and thus deserve a careful study, in addition to its usefulness to determine the quantitative amount of temporal DC current in the clinical trials. A stimulating system consists of power supply, Pt-electrodes, 6-well plates, etc. To ablate adsorption and desorption of electrode materials to directly affect tumor cells or its tissues and perform faradaic processes on electrodes, electrodes of pure platinum are used.
Sponsorship	Plasma Sci. and Applications Committee of the IEEE Nuclear and Plasma Sci. Soc
File Size	66276
File Format	PDF
ISBN	0780383346
ISSN	07309244
DOI	10.1109/PLASMA.2004.1339776
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-07-01
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Neoplasms Electrodes DNA Diseases Drugs Clinical trials Power supplies Biological materials Tumors Platinum
Content Type	Text
Resource Type	Article
Subject	Atomic and Molecular Physics, and Optics Condensed Matter Physics Electrical and Electronic Engineering

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