NDLI: Suppression of random coincidences during in-beam PET measurements

Content Provider	IEEE Xplore Digital Library
Author	Crespo, P. Barthel, T. Frais-Kolbl, H. Griesmayer, E. Heidel, K. Parodi, K. Pawelke, J. Enghardt, W.
Copyright Year	2004
Description	Author affiliation: Inst. of Nucl. & Hadron Phys., Forschungszentrum Rossendorf, Dresden, Germany (Crespo, P.; Barthel, T.)
Abstract	In-beam positron emission tomography (PET) is currently the only method for an in-situ monitoring of charged hadron therapy. However, in-beam PET data, measured at beams with a sub-/spl mu/s-microstructure due to the accelerator radiofrequency (RF), are highly corrupted by random coincidences arising from prompt /spl gamma/-rays following nuclear reactions as the projectiles penetrate the tissue. Therefore, since random-correction techniques from conventional PET cannot be applied, the clinical in-beam PET at the therapy facility at the Gesellschaft fur Schwerionenforschung (GSI) Darmstadt merely reconstructs events registered in the pauses (/spl sim/2-4 s) between the beam macropulses (/spl les/2 s). We have successfully tested at GSI two methods for suppressing, during beam extraction, the micropulse-induced random coincidences. Image statistics increased /spl sim/90%. Both methods rely on the synchronization of the /spl gamma//spl gamma/-coincidences measured by the positron camera with the time microstructure of the beam, either by using the RF-signal from the accelerator or the signal of a thin diamond detector placed in the beam path in front of the target. Energy and triple-coincidence time correlated spectra first-measured during beam extraction, combined with the corresponding tomographic images of the /spl beta//sup +/-activity induced by the beam in a plastic phantom, clearly confirm the feasibility of the proposed random suppression methods. These methods provide the solution for applying in-beam PET at future synchrotron and even cyclotron facilities with reduced beam acceleration (delivery pause) times.
Starting Page	2226
Ending Page	2230
File Size	846554
Page Count	5
File Format	PDF
ISBN	0780387007
ISSN	10823654
e-ISBN	0780387015
DOI	10.1109/NSSMIC.2004.1462704
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-10-16
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Particle beams Medical treatment Radio frequency Monitoring Nuclear measurements Particle beam measurements Projectiles Image reconstruction Testing
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Suppression of random coincidences during in-beam PET measurements at ion beam radiotherapy facilities

Proton therapy in combination with PET as monitor: a feasibility study

A Method for System Matrix Construction and Processing for Reconstruction of In-Beam PET Data

Reduction of random coincidences in small animal PET using Artificial Neural Networks

On the optimum strategy for subsets based reconstruction of in-beam PET data

Influence of the time of flight information on the reconstruction of in-beam PET data

On-line monitoring and PET imaging of proton radiotherapy beams

Dosimetry by means of in-beam PET with RI beam irradiation

Optimum voxel size for reconstruction of in-beam PET data

Suppression of random coincidences during in-beam PET measurements

Similar Documents

Suppression of random coincidences during in-beam PET measurements at ion beam radiotherapy facilities

Proton therapy in combination with PET as monitor: a feasibility study

A Method for System Matrix Construction and Processing for Reconstruction of In-Beam PET Data

Reduction of random coincidences in small animal PET using Artificial Neural Networks

On the optimum strategy for subsets based reconstruction of in-beam PET data

Influence of the time of flight information on the reconstruction of in-beam PET data

On-line monitoring and PET imaging of proton radiotherapy beams

Dosimetry by means of in-beam PET with RI beam irradiation

Optimum voxel size for reconstruction of in-beam PET data

Suppression of random coincidences during in-beam PET measurements