NDLI: Comparison of imaging characteristics of Xe-133 and Xe-127 for use in dynamic brain SPECT: a Monte Carlo investigation

Content Provider	IEEE Xplore Digital Library
Author	Pretorius, P.H. Glick, S.J. De Vries, D.J. Licho, R. King, M.A.
Copyright Year	2000
Description	Author affiliation: Massachusetts Univ. Med. Center, Worcester, MA, USA (Pretorius, P.H.)
Abstract	The aim of the study was to determine the degree of improvement obtained by using Xe-127 as the imaging agent compared to Xe-133 for rCBF SPECT. The SIMIND Monte Carlo code was used to simulate projections of gray and white matter at a ratio of 4:1 using a realistic voxelized anthropomorphic brain phantom. Xe-133 and Xe-127 were simulated using high-sensitivity and medium-energy collimators respectively. Data were acquired into 64 projections of 128/spl times/128 matrix size. A Tc-99m HMPAO study was simulated as reference. Contrast calculations yielded values of 2.1:1, 1.8:1, and 1.3:1 between gray and white matter for Tc-99m, Xe-127, and Xe-133 respectively. A normalized profile through a transverse mid-brain slice demonstrates the improvement in resolution with Xe-127 compared to Xe-133. The difference in resolution between Tc-99m and Xe-127 are less pronounced. Further investigation is needed to study the noise characteristics of both Xenon isotopes for clinical rCBF studies. With Xe-127 and an optimized medium-energy high-resolution fan-beam collimator, it is likely that a notable increase in quantitative accuracy of rCBF estimation can be realized.
Starting Page	1005
Ending Page	1008
File Size	378688
Page Count	4
File Format	PDF
ISBN	0780356969
ISSN	10823654
DOI	10.1109/NSSMIC.1999.845831
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1999-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Single photon emission computed tomography Brain modeling Xenon Monte Carlo methods Biomedical imaging Collimators Isotopes Electromagnetic scattering Particle scattering Positron emission tomography
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

3-D Monte Carlo-based scatter compensation in quantitative I-131 SPECT reconstruction

Accurate modeling of fan-beam collimators in brain SPECT imaging using Monte Carlo simulation

Fast Monte Carlo Simulation Based Joint Iterative Reconstruction for Simultaneous 99mTc/123I Brain SPECT Imaging

Efficient photon cross-talk calculation in SPECT

Fast Monte Carlo simulation method for medium- and high-energy SPECT

Out-of-plane Photons In SPECT

Impact of attenuation, scatter and depth dependent collimator response correction in 3-D cardiac SPECT imaging: a Monte Carlo investigation

Collimator-detector response compensation in quantitative SPECT reconstruction

Evaluation of rotating slant-hole SPECT mammography using Monte-Carlo simulation methods

Comparison of imaging characteristics of Xe-133 and Xe-127 for use in dynamic brain SPECT: a Monte Carlo investigation

Similar Documents

3-D Monte Carlo-based scatter compensation in quantitative I-131 SPECT reconstruction

Accurate modeling of fan-beam collimators in brain SPECT imaging using Monte Carlo simulation

Fast Monte Carlo Simulation Based Joint Iterative Reconstruction for Simultaneous 99mTc/123I Brain SPECT Imaging

Efficient photon cross-talk calculation in SPECT

Fast Monte Carlo simulation method for medium- and high-energy SPECT

Out-of-plane Photons In SPECT

Impact of attenuation, scatter and depth dependent collimator response correction in 3-D cardiac SPECT imaging: a Monte Carlo investigation

Collimator-detector response compensation in quantitative SPECT reconstruction

Evaluation of rotating slant-hole SPECT mammography using Monte-Carlo simulation methods

Comparison of imaging characteristics of Xe-133 and Xe-127 for use in dynamic brain SPECT: a Monte Carlo investigation