NDLI: The effect of contraction and twist on myocardial PET and SPECT image resolution: a mathematical phantom study

Content Provider	IEEE Xplore Digital Library
Author	Smith, M.F.
Copyright Year	2000
Description	Author affiliation: Dept. of Nucl. Med., Nat. Inst. of Health, Bethesda, MD, USA (Smith, M.F.)
Abstract	Motion of the heart degrades cardiac PET and SPECT resolution. A mathematical phantom was constructed to model contractile and non-uniform twisting motions of the left ventricular myocardium as the heart beats. The phantom was used to estimate the effect of motion on cardiac ECT image resolution and on quantitation in regions of interest (ROIs). Cardiac motion with contraction and twist was simulated at 16 time gates. The movement of mid-myocardial points was tracked, from which motion blur was computed. Contractile motion was greater near the base and twisting motion was greater near the apex. The blur due to both motions was equivalent to 7-9 mm FWHM Gaussian smoothing. Clinical PET resolution of 7 mm was degraded to 10-11 mm FWHM and clinical SPECT resolution of 14 mm to 16-17 mm FNHM. Weighting coefficients were used to characterize how activity in short and long axis ROIs was related to activity in source model ROIs. The effect of contraction was dependent on whether short or long axis slices were used for ROIs and on the spatial location of the ROIs. The weights for short axis ROIs showed the effect of twist in blurring activity to adjacent angular sectors. This effect was not seen in long axis ROIs where the angular range encompassed by the constant thickness slices was greater. A mathematical heart phantom that models contractile and twisting motions is valuable for investigating the effect of these motions on cardiac ECT studies.
Starting Page	1255
Ending Page	1259
File Size	479255
Page Count	5
File Format	PDF
ISBN	0780356969
ISSN	10823654
DOI	10.1109/NSSMIC.1999.842785
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1999-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Myocardium Positron emission tomography Imaging phantoms Degradation Mathematical model Electrical capacitance tomography Heart beat Motion estimation Image resolution Computational modeling
Content Type	Text
Resource Type	Article

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