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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Berger, T.W. |
| Copyright Year | 2004 |
| Description | Author affiliation: Center for Neural Eng., Univ. of Southern California, Los Angeles, CA, USA (Berger, T.W.) |
| Abstract | Summary form only given. Dr. Berger and his colleagues at the University of Southern California are working to develop a microchip-based neural prosthetic for the hippocampus, a region of the brain responsible for the formation of long-term memories, and that frequently is damaged as a result of head trauma, epilepsy, stroke, and Alzheimer's disease. The various goals of this effort include: (1) experimental study of neuron and neural network function - how does the brain encode information?, (2) formulation of biologically realistic models of neural system dynamics - can that encoding process be described mathematically so that we can predict how the brain respond to a particular event?, (3) microchip implementation of neural system models - can the mathematical model be realized as a set of electronic circuits to achieve rapid computational speed and miniaturization?, and (4) hybrid neuron-silicon interfaces - can electronic devices be "connected" to neural tissue for bi-directional communication with the brain?. Described as part of the latter effort are recent successes in growing living neurons directly onto silicon-based computer chips. Dr. Berger describes a proof-of-principle of the vision of utilizing biomimetic electronics to restore lost brain function using a hippocampal brain slice preparation. Dr. Berger also describes how the current work in brain slices can be extended to behaving animals in the near future. |
| File Size | 42940 |
| File Format | |
| ISBN | 0780383591 |
| ISSN | 10987576 |
| DOI | 10.1109/IJCNN.2004.1380845 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2004-07-25 |
| Publisher Place | Hungary |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Biomimetics Diseases Mathematical model Neurons Biological system modeling Brain modeling Predictive models Prosthetics Hippocampus Epilepsy |
| Content Type | Text |
| Resource Type | Article |
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