NDLI: Functionalization of Carbon Nanotubes with Antibodies for Breast Cancer Detection Applications

Content Provider	IEEE Xplore Digital Library
Author	Sirdeshmukh, R. Teker, K. Panchapakesan, B.
Copyright Year	2004
Description	Author affiliation: University of Delaware (Sirdeshmukh, R.)
Abstract	We study the effect of functionalization of Carbon Nanotubes (CNTs) with a primary monoclonal mouse immunoglobin G (IgG) specific to the cell-surface receptors of breast cancer cells, and secondary polyclonal goat ant- mouse IgG. The CNTs, in solution with a surfactant (sodium dodecyl benzene sulfonate) were labeled with dihexyloxacarbocyanine iodide (DiOC6), a fluorescent dye, in order to view them with fluorescently labeled antibodies through confocal microscopy. Co-localization for CNTs in combination with the primary antibody conjugated to the secondary was determined to be 90%, whereas CNTs in combination with the secondary antibody and polyethylene glycol (PEG), a polymer used to block CNTs from proteins binding to their surface, was found to be very minimal (0.5%). Preliminary studies on the electrical measurements of the primary mouse IgG incubated with CNTs show a decrease in conductance compared to that of bare CNT field effect transistors (CNTFETs). This observed change in conductance, can eventually be amplified and utilized in applications leading to a full-fledged breast cancer detection system in the future.
Starting Page	48
Ending Page	53
File Size	921480
Page Count	6
File Format	PDF
ISBN	0769521894
DOI	10.1109/ICMENS.2004.1508911
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-08-25
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Carbon nanotubes Breast cancer Cancer detection Mice Fluorescence Microscopy Polyethylene Polymers Proteins Electric variables measurement
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Antibody functionalization of carbon nanotubes for breast cancer applications

Confocal Microscopy of Bioconjugated Carbon Nanotubes for Biosensor Applications

Carbon nanotubes synthesized by plasma enhanced CVD: Preparation for measurements of their electrical properties for application in pressure sensor

Molecular recognition using corona phase complexes made of synthetic polymers adsorbed on carbon nanotubes

Biomolecular Tuning of Electronic Transport Properties of Carbon Nanotubes via Antibody Functionalization

Electrical and Optical Properties of Carbon Nanotubes Characterized by Terahertz Electromagnetic Pulses

Property of polyaniline /multi-wall carbon nanotube composites

Carbon nanotube labeled immunosensor for lateral flow diagnostics

Single Carbon Nanotube Based Ion Sensor for Gas Detection

Functionalization of Carbon Nanotubes with Antibodies for Breast Cancer Detection Applications

Similar Documents

Antibody functionalization of carbon nanotubes for breast cancer applications

Confocal Microscopy of Bioconjugated Carbon Nanotubes for Biosensor Applications

Carbon nanotubes synthesized by plasma enhanced CVD: Preparation for measurements of their electrical properties for application in pressure sensor

Molecular recognition using corona phase complexes made of synthetic polymers adsorbed on carbon nanotubes

Biomolecular Tuning of Electronic Transport Properties of Carbon Nanotubes via Antibody Functionalization

Electrical and Optical Properties of Carbon Nanotubes Characterized by Terahertz Electromagnetic Pulses

Property of polyaniline /multi-wall carbon nanotube composites

Carbon nanotube labeled immunosensor for lateral flow diagnostics

Single Carbon Nanotube Based Ion Sensor for Gas Detection

Functionalization of Carbon Nanotubes with Antibodies for Breast Cancer Detection Applications