NDLI: Accurate 3D source localization of focal epileptic foci using interictal EEG spikes

Content Provider	IEEE Xplore Digital Library
Author	Cabrerizo, M. Goryawala, M. Jayakar, P. Barreto, A. Khizroev, S. Adjouadi, M.
Copyright Year	2011
Description	Author affiliation: Department of Electrical & Computer Engineering, Center for Advance Technology and Education, Florida International University, 10555 W. Flagler Street, Miami 33174, USA (Cabrerizo, M.; Goryawala, M.; Barreto, A.; Khizroev, S.; Adjouadi, M.) \|\| Brain Institute Department, Miami Children's Hospital, 3100 S.W. 62nd Avenue, FL 33155, USA (Jayakar, P.)
Abstract	The goal of any surgery is the patient's complete recovery with maximum relief and minimal adverse effects. This goal is less complicated when epilepsy is predicated on tumor location revealed through standard imaging studies, in which case noninvasive post surgical studies can relate the 3D source with the area of the tumor that was removed. Success is more difficult, however, in non-lesional cases, where the characteristics of the epilepsy event are more difficult to define. This challenge reinforces the need for accurate 3D source localization to guarantee success of the first surgical intervention. Through this major undertaking which integrates recording modalities in time and space, clinicians and surgeons become more confident at prescribing a resection, especially when markers for the epileptogenic area and related brain functional assessments are consistent with the area thought to be the cause of the diagnosed neurological problem. This study evaluates the utility of 3D localization of interictal spike activity on the electroencephalographs (EEG) superimposed on magnetic resonance imagery (MRI) in a pediatric population. The results show a 99% concordance between EEG source localization and the suggested epileptogenic zone
Starting Page	1
Ending Page	6
File Size	995196
Page Count	6
File Format	PDF
ISBN	9781467303712
e-ISBN	9781467303729
DOI	10.1109/SPMB.2011.6120106
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-12-10
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Electrodes Interictal spikes Magnetic resonance imaging Epileptic focus Brain modeling Electroencephalography Three dimensional displays Mathematical model Equations 3-D source localization
Content Type	Text
Resource Type	Article

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