NDLI: Assessment of prolonged tissue response to porousiron implant by radiodensity approach

Content Provider	IEEE Xplore Digital Library
Author	Siallagan, Sitaria Fransiska Gunanti Sariningrum, Arlita Paramitha, Devi Ulum, Mokhamad Fakhrul Hermawan, Hendra Noviana, Deni
Copyright Year	2015
Description	Author affiliation: Department of Mining, Metallurgical and Materials Engineering and CHU de Quebec Research Center, Laval University, Quebec City, Canada (Paramitha, Devi; Hermawan, Hendra) \|\| Faculty of Veterinary Medicine, Bogor Agricultural University, Indonesia (Sariningrum, Arlita) \|\| Department of Veterinary Clinic, Reproduction, and Pathology, Indonesia (Siallagan, Sitaria Fransiska; Gunanti; Ulum, Mokhamad Fakhrul; Noviana, Deni)
Abstract	Porous iron has been recently introduced as new biomaterials for bone scaffolds. As a metal that degrades in the in vivo setting (biodegradable metal), little has been known for its cell-material interaction within the living tissue especially in the view of its applications for bone implant materials. Therefore, the aim of this study is to assess tissue response to the implantation of porous iron in the in vivo setting using rats as animal model and radiographic examination. Ten adult Sprague Dawley rats received the implantation of porous iron implants having different porosity into their femoral bone followed by radiographic examination up to 5 months post-implantation. Results shows differences in the opacity of radiographic images where the implants looked more radiopaque than bone and muscle. Radiodensity values of the implants decreases overtime indicating they experienced progressive degradation. This values dynamically change over time up to 5 months in relation to the event of chronic inflammation, degradation and bone healing process.
Starting Page	237
Ending Page	240
File Size	306252
Page Count	4
File Format	PDF
e-ISBN	9781467378000
DOI	10.1109/ICICI-BME.2015.7401369
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-11-02
Publisher Place	Indonesia
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Degradation Radiography Rat Implants Muscles Rats Porous iron Bones Iron Biodegradable metal Bone implant Biomaterials
Content Type	Text
Resource Type	Article

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