NDLI: Mid-infrared opto-nanofluidics for label-free on-chip sensing

Content Provider	IEEE Xplore Digital Library
Author	Pao Tai Lin Sen Wai Kwok Lin, H.-Y.G. Singh, V. Kimerling, L.C. Whitesides, G.M. Agarwal, A.
Copyright Year	2014
Description	Author affiliation: Microphotonics Center, Massachusetts Inst. of Technol., Cambridge, MA, USA (Pao Tai Lin; Singh, V.; Kimerling, L.C.; Agarwal, A.) \|\| Dept. of Chem. & Chem. Biol., Harvard Univ., Cambridge, MA, USA (Sen Wai Kwok; Whitesides, G.M.) \|\| Center for Nanoscale Syst., Harvard Univ., Cambridge, MA, USA (Lin, H.-Y.G.)
Abstract	A mid-infrared (mid-IR) label-free chemical sensor was developed using opto-nanofluidics consisting of a Si-liquid-Si slot-structure. A broadband mid-IR lightwave can be strongly confined within a nanofluidic capillary by utilizing the large refractive index contrast (Δn ~ 2) between the liquid core waveguide and the Si cladding. Through an optical-field enhancement together with a direct interaction between the probe light and the analyte, the sensitivity for chemical detection is increased by 50 times when compared to evanescent-wave sensing. This spectral characterization distinguished several common organic liquids (e.g., n-bromohexane, toluene, isopropanol) accurately, and could determine the ratio of chemical species (e.g., acetonitrile and ethanol) at low concentration (<; 5 μL/mL) in a mixture through spectral scanning over their characteristic mid-IR absorption peaks. The combination of CMOS-compatible planar mid-IR microphotonics, and a high-throughput nanofluidic sensor system, provides a unique platform for chemical detection.
Starting Page	1
Ending Page	2
File Size	318311
Page Count	2
File Format	PDF
ISBN	9781557529992
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2014-06-08
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	The Optical Society
Subject Keyword	Sensitivity Nanofluidics Optical sensors Chemicals Optical waveguides Optical surface waves
Content Type	Text
Resource Type	Article

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