NDLI: Quantitation of regional myocardial blood flow by contrast echocardiography

Content Provider	IEEE Xplore Digital Library
Author	Mor-Avi, V. David, D. Bitton, Y. Akselrod, S.
Copyright Year	1992
Description	Author affiliation: Med. Phys., Tel Aviv Univ., Israel (Mor-Avi, V.)
Abstract	A basic theoretical approach is presented for the quantitative measurement of regional myocardial tissue blood flow based on the computer analysis of contrast enhanced echocardiographic images. Blood flow is evaluated as the ratio of the intravascular fraction, and the mean transit time of the contrast agent. Both parameters are obtained by analyzing the variations in mean videointensity in two regions of interest, defined in the left ventricular (LV) cavity and the myocardial tissue. The main transit time is computed using combined time- and frequency-domain processing, applying deconvolution of the response function. Extensive computer simulation showed that the algorithm successfully evaluates the mean transit time within 10% of error for signal-to-noise levels up to 2:1. The intravascular volume fraction is computed as a ratio of the integrated intensities in the two regions of interest. Animal experiments involving radiolabeled microspheres showed high correlation between the two independent measurements of blood flow.<>
Starting Page	199
Ending Page	202
File Size	331015
Page Count	4
File Format	PDF
ISBN	0818635525
DOI	10.1109/CIC.1992.269412
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1992-10-11
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Myocardium Blood flow Echocardiography Biomedical imaging Humans Muscles Fluid flow measurement Microscopy Heart beat Physics
Content Type	Text
Resource Type	Article

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