NDLI: CAD of osteoporosis in vertebrae using dual-energy CT

Content Provider	IEEE Xplore Digital Library
Author	Wesarg, S. Erdt, M. Kafchitsas, K. Khan, M.F.
Copyright Year	2010
Description	Author affiliation: Dept. Cognitive Computing & Medical Imaging, Fraunhofer IGD, Darmstadt, Germany (Kafchitsas, K.) \|\| Interactive Graphics Systems Group (GRIS) Technische Universität Darmstadt, Germany (Wesarg, S.) \|\| Clinic and Policlinic for Orthopedics and Orthopedic Surgery, Universitätsmedizin Mainz, Germany (Erdt, M.) \|\| Institute for Diagnostic and Interventional Radiology, Goethe University, Frankfurt/M., Germany (Khan, M.F.)
Abstract	The assessment of bone mineral density (BMD) in vertebrae is critical for the diagnosis of osteoporosis. Recent developments in dual-source CT allow for the simultaneous acquisition of two image data sets with different X-ray tube energies — dual-energy CT (DECT). We present a comprehensive approach for assessing the density of the trabecular bone in vertebrae of the spine based on DECT image data. For this, we apply and combine methods from different areas: the deformation of a template mesh for delineating the structures of interest, a biophysical model of the trabecular bone for the computation of BMD values, and different visualization approaches for the display of the results. In addition, we investigate the correlation between the computed BMD values with concurrently measured pull-out forces for pedicle screws. We show that there is a linear correlation between both measures and thus, DECT provides correct BMD values for the trabecular bone. We conclude that our approach enables the radiologist to diagnose osteoporosis based on DECT image data which has the potential to replace the current gold standard dual-energy X-ray absorp-tiometry.
Starting Page	358
Ending Page	363
File Size	1202162
Page Count	6
File Format	PDF
ISBN	9781424491674
ISSN	10637125
e-ISBN	9781424491681
DOI	10.1109/CBMS.2010.6042670
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-12
Publisher Place	Australia
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Bones Fasteners Three dimensional displays Osteoporosis Image color analysis Correlation Computed tomography
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Computer Science Applications

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