NDLI: A segmentation method for carotid artery atherosclerosis plaque for MRI contrast and MRI features, oxidative stress markers in coronary and carotid plaque

Content Provider	IEEE Xplore Digital Library
Author	Sharma, R. Singh, R.B. Gupta, R.K.
Copyright Year	2003
Description	Author affiliation: Dept. of Medicine, Columbia Univ., New York, NY, USA (Sharma, R.)
Abstract	A segmentation framework is proposed to determine the wall thickness, carotid artery plaque volume as morphological markers. MRI features, NMR peaks, oxidative stress markers as MRI-clinical correlates were compared in carotid and coronary plaques. The objective is to distinguish plaque components by their different MR image intensities at different image contrasts using in vivo and ex-vivo images; to segment and quantify plaque components (area and volume) using plaque contour; to compare NMR peaks, MRI features, relaxation times and oxidative stress markers in coronary and carotid endarterectomy samples to implicate plaque as lipid disorder. Fourteen pairs of coronary and ten pairs of carotid arteries after FSE T1 weighted MRI examination from post-surgery donors (aged 42 to 68 years) were analyzed for lipid proton NMR peaks and tissue oxidative stress markers. Ten pairs met the criteria for rigorous analysis. Carotid artery wall thickness and plaque volumes were measured from the MRI images. In vitro NMR peaks and oxidative stress markers were computed in both coronary and carotid artery samples. The carotid artery bifurcation is a site at which MRI can monitor plaque progression reproducibly. Total wall volumes of carotid arteries in vivo and in vitro were moderately correlated (concordance correlation coefficient r/sub c/=0.71). Correlation was measured for atheroma scores (r/sub c/=0.954); and plaque volume scores (r/sub c/=0.942). The observation of comparable NMR lipid peaks and oxidative stress suggested that diagnostic information about atherosclerosis progression in both coronary and carotid arteries may be similar. Carotid artery plaque features were MRI visible and predictive of plaque rupture and stability. Oxidative stress markers were significant in carotid artery tissues and comparable to coronary tissues. Lipid NMR peaks were significant suggestive of lipid accumulation in atherosclerosis of the human carotid arteries as a lipid disorder.
Sponsorship	IEEE Comput. Soc. Tech. Committee on Computational Med. Mount Sinai School of Med. Dept. Anesthesiology Texas Tech. Univ. College of Eng
Starting Page	323
Ending Page	328
File Size	628578
Page Count	6
File Format	PDF
ISBN	0769519016
ISSN	10637125
DOI	10.1109/CBMS.2003.1212809
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-06-26
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Magnetic resonance imaging Carotid arteries Atherosclerosis Stress Nuclear magnetic resonance Lipidomics Image segmentation In vivo Volume measurement In vitro
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Computer Science Applications

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Automated segmentation of the individual branches of the carotid arteries in contrast-enhanced MR angiography using DeepMedic

Three-dimensional Ultrasound Imaging of Carotid Atherosclerosis

Association of carotid artery parameters of atherosclerosis in coronary artery disease.

A Device for MR Imaging of Atherosclerosis Plaque in Carotid Endarterectomy Specimens Ex Vivo

Estimation of carotid atherosclerotic plaque volume from in vivo magnetic resonance images

Carotid artery segmentation and plaque quantification in CTA

Sudden Death in Coronary Artery Disease are Associated With High 3D Critical Plaque Wall Stress: A 3D Multi-Patient FSI Study Based on Ex Vivo MRI of Coronary Plaques

Atherosclerotic carotid plaque segmentation

MR Imaging in Carotid Artery Atherosclerosis Plaque Characterization

A segmentation method for carotid artery atherosclerosis plaque for MRI contrast and MRI features, oxidative stress markers in coronary and carotid plaque

Similar Documents

Automated segmentation of the individual branches of the carotid arteries in contrast-enhanced MR angiography using DeepMedic

Three-dimensional Ultrasound Imaging of Carotid Atherosclerosis

Association of carotid artery parameters of atherosclerosis in coronary artery disease.

A Device for MR Imaging of Atherosclerosis Plaque in Carotid Endarterectomy Specimens Ex Vivo

Estimation of carotid atherosclerotic plaque volume from in vivo magnetic resonance images

Carotid artery segmentation and plaque quantification in CTA

Sudden Death in Coronary Artery Disease are Associated With High 3D Critical Plaque Wall Stress: A 3D Multi-Patient FSI Study Based on Ex Vivo MRI of Coronary Plaques

Atherosclerotic carotid plaque segmentation

MR Imaging in Carotid Artery Atherosclerosis Plaque Characterization

A segmentation method for carotid artery atherosclerosis plaque for MRI contrast and MRI features, oxidative stress markers in coronary and carotid plaque