NDLI: Urea kinetic modelling: new hemodialysis prescription procedure

Content Provider	IEEE Xplore Digital Library
Author	Prado, M. Roa, L.M. Palma, A. Milan, J.A.
Copyright Year	2000
Description	Author affiliation: Biomed. Eng. Group, Seville Univ., Spain (Prado, M.)
Abstract	The National Cooperative Dialysis Study (NCDS) showed the viability of the single-pool urea kinetic model (spUKM) to maintain the blood urea nitrogen (BUN) level of the renal patient in an adequate target interval, defining the single-pool normalized clearance of urea spKt/V as an index of the hemodialysis dose. However, the urea distribution is a nonuniform problem, due to the barriers between pools in the body distribution volume. The urea rebound induced by the hemodialysis is a consequence of this nonuniform distribution and limits the applicability of the NCDS. The viability of a more recent index, the equilibrated Kt/V (eKt/V), is being studied, because it is not affected by the urea rebound. This index is defined substituting the postdialysis BUN by equilibrated BUN (measured about an hour from the end of hemodialysis). In spite of its good results to calculate the hemodialysis dose in the presence of urea rebound, the eKt/V is unable to prescribe a hemodialysis, because the equilibrated clearance is different to the dialyzer clearance. We present a new hemodialysis prescribing procedure which calculates the adequate dialyzer clearance to obtain a target time averaged concentration of urea. This procedure is supported by a new model that we have developed: the normalized single-pool urea kinetic model (spUKM/sup norm/), which is able to calculate a good approximation to the real Kt/V based in dialyzer clearance. The eKt/V and spKt/V are used in intermediate steps of our procedure, and so the actual advances in these indexes can be taken into account.
Starting Page	1092
Ending Page	1095
File Size	353697
Page Count	4
File Format	PDF
ISBN	0780364651
ISSN	1094687X
DOI	10.1109/IEMBS.2000.897918
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2000-07-23
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Kinetic theory Equations Medical treatment Blood Switches High definition video Nitrogen Mathematical model Parameter estimation Boundary conditions
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Experimental determination of urea kinetics parameters during hemodialysis

Model selection for urea kinetics in dialysis therapy

A new analytic model of urea kinetics oriented to parameter estimation

Robust estimation of urea concentration during dialytic treatment

Kinetic indices and dialysis outcomes

A new method for 2-D AR model parameter estimation

Kinetic Modelling and Parameter Estimation for the Bulk Free Radical Addition Homopolymerizations of Methyl Methacrylate and Styrene

Optimal hemodialysis programming by a mathematical model

Parameter identification of bacterial growth bioprocesses

Urea kinetic modelling: new hemodialysis prescription procedure

Similar Documents

Experimental determination of urea kinetics parameters during hemodialysis

Model selection for urea kinetics in dialysis therapy

A new analytic model of urea kinetics oriented to parameter estimation

Robust estimation of urea concentration during dialytic treatment

Kinetic indices and dialysis outcomes

A new method for 2-D AR model parameter estimation

Kinetic Modelling and Parameter Estimation for the Bulk Free Radical Addition Homopolymerizations of Methyl Methacrylate and Styrene

Optimal hemodialysis programming by a mathematical model

Parameter identification of bacterial growth bioprocesses

Urea kinetic modelling: new hemodialysis prescription procedure