NDLI: Late potential analysis in Chagas disease using the vector spectral combination of orthogonal leads

Content Provider	IEEE Xplore Digital Library
Author	Bravo, R. Escalona, O. Mora, F. Passariello, G.
Copyright Year	1997
Description	Author affiliation: GBBA, Simon Bolivar Univ., Caracas, Venezuela (Bravo, R.)
Abstract	Chagas disease is a major public health problem in South American countries, in the Venezuelan case, the heart is the mainly affected organ. The parasite that produces the disease invades the myocardium, causes muscle and conduction system degeneration, leading to abnormal ventricular contractility and conduction. Late potential (LP) analysis can detect abnormal electric behavior of the ventricles, which has been correlated with the presence of ventricular tachycardia episodes. Time domain methods for LP analysis are widely used but they are affected by other cardiac pathologies, i.e., branch blocks (BE), which are found simultaneously with abnormal ventricular conduction phenomena in chagasic patients. The use of an orthogonal lead vectorspectral combination using the Hartley transform has demonstrated to be a simple frequency domain method for the interpretation of abnormal ventricular potentials. This work uses the latter approach for LP analysis of high resolution ECG (HRECG) records of chagasic patients. The vectorspectral magnitude (S) was computed as the sum of the DHT spectra components of the XYZ leads in the frequency bands of 60 to 300 Hz and -300 to -60 Hz, for each chagasic patient group and a healthy subject control group in a time window at the end of QRS. Results showed that S is significantly lower in healthy subjects (63.5/spl plusmn/23.8 /spl mu/V) than in chagasic patients with abnormal electrocardiogram (89.2/spl plusmn/43.7 /spl mu/V), p<0.05. The vector spectral analysis is a simple frequency domain method for LP study, the results showed that the method can detect positive patients with generalized myocardial disease.
Starting Page	78
Ending Page	80
File Size	289755
Page Count	3
File Format	PDF
ISBN	0780342623
ISSN	1094687X
DOI	10.1109/IEMBS.1997.754468
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1997-10-30
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cardiac disease Cardiovascular diseases Degenerative diseases Parasitic diseases Myocardium Frequency domain analysis Public healthcare Heart Muscles Time domain analysis
Content Type	Text
Resource Type	Article

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