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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Rongjie Lai Yonggang Shi Sicotte, N. Toga, A.W. |
| Copyright Year | 2011 |
| Description | Author affiliation: Department of Neurology, University of California, Los Angeles, USA (Yonggang Shi; Toga, A.W.) || Department of Mathematics, University of Southerm California, USA (Rongjie Lai) || Cedar Sinai Medical Center, Los Angeles, U. S. A. (Sicotte, N.) |
| Abstract | Corpus callosum (CC) is an important structure in human brain anatomy. In this work, we propose a fully automated and robust approach to extract corpus callosum from T1-weighted structural MR images. The novelty of our method is composed of two key steps. In the first step, we find an initial guess for the curve representation of CC by using the zero level set of the first nontrivial Laplace-Beltrami (LB) eigenfunction on the white matter surface. In the second step, the initial curve is deformed toward the final solution with a geodesic curvature flow on the white matter surface. For numerical solution of the geodesic curvature flow on surfaces, we represent the contour implicitly on a triangular mesh and develop efficient numerical schemes based on finite element method. Because our method depends only on the intrinsic geometry of the white matter surface, it is robust to orientation differences of the brain across population. In our experiments, we validate the proposed algorithm on 32 brains from a clinical study of multiple sclerosis disease and demonstrate that the accuracy of our results. |
| Starting Page | 2034 |
| Ending Page | 2040 |
| File Size | 1098838 |
| Page Count | 7 |
| File Format | |
| ISBN | 9781457711015 |
| ISSN | 15505499 |
| e-ISBN | 9781457711022 |
| DOI | 10.1109/ICCV.2011.6126476 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2011-11-06 |
| Publisher Place | Spain |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Eigenvalues and eigenfunctions Robustness Geometry Sparse matrices Image segmentation Multiple sclerosis Symmetric matrices |
| Content Type | Text |
| Resource Type | Article |
| Subject | Computer Vision and Pattern Recognition Software |
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