NDLI: Interactive navigation through glial cells

Content Provider	IEEE Xplore Digital Library
Author	Meyer, J. Hagen, H. Lohr, C. Deitmer, J.W.
Copyright Year	1998
Description	Author affiliation: Comput. Graphics Dept., Kaiserslautern Univ., Germany (Meyer, J.)
Abstract	Glial cells express a large variety of bio-electric and bio-chemical phenomena. A quantitative analysis shows that the brain consists of about 10 to 50 times more glial cells than neurons. Similar to neurons, glial cells implement voltage-dependent and ligand-gated membrane channels. Neurotransmitter receptors associated with ion-selective membrane channels have been described in several types of macroglial cells. Leech giant glial cells provide a good example for studying structural and physiological properties of this cell type. Confocal laser-scanning microscopy generates images from cutting (i.e. focus) planes of the object, in a way that, by varying the focus plane, the object can be resolved and scanned serially at several levels. Artifacts, such as transparent, low contrast, and blurred or fuzzy structures from neighboring slices must be filtered in order to reveal the capillary structure of the cell. With the microscope, the object cannot be rotated by ninety degrees, perpendicular to the viewing direction. Once scanned, the viewing direction cannot be altered any more. Computer graphics allows projections from any perspective angle, so that the cell can be studied in full detail. A visualization system should provide a flexible environment for interactively exploring the cell. Therefore, we have extended our InVIS (Interactive Visualization) system, which has been originally designed for medical applications (CT and MRI), to confocal microscopy. We describe the structure of our system and the addition of new features.
Starting Page	73
Ending Page	77
File Size	779611
Page Count	5
File Format	PDF
ISBN	0818684453
DOI	10.1109/CGI.1998.694252
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1998-06-26
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Navigation Microscopy Neurons Biomembranes Focusing Visualization Bioelectric phenomena Voltage Neurotransmitters Laser beam cutting
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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