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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Huang, Y.M. Uppalapati, M. Hancock, W.O. Jackson, T.N. |
| Copyright Year | 2004 |
| Description | Author affiliation: Dept. of Electr. Eng., Pennsylvania State Univ., University Park, PA, USA (Huang, Y.M.) |
| Abstract | Kinesins are molecular motors that move along microtubules, and provide a model system for force generation that can be exploited for kinesin-powered nano- and micro-machines. Microtubules are /spl sim/25 nm diameter cylindrical polymers of the protein tubulin and can be nm to /spl mu/m long. Kinesins bind to microtubules and use the energy of ATP hydrolysis to walk unidirectionally along them at speeds of /spl sim/1 /spl mu/m/s. In this work, we reverse the typical biological system and move microtubules along surfaces functionalized with kinesin motors. The microtubules then become potential transport vehicles for sensors and lab-on-a-chip applications. A key requirement for extracting useful work from this system is confinement and control of the movement of microtubules over kinesin coated surfaces. |
| Starting Page | 185 |
| Ending Page | 186 |
| File Size | 132411 |
| Page Count | 2 |
| File Format | |
| ISBN | 0780382846 |
| ISSN | 15483770 |
| DOI | 10.1109/DRC.2004.1367852 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2004-06-21 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Glass Microchannel Resists Substrates Micromotors Nanobioscience Silicon Biological materials Nanoscale devices Biosensors |
| Content Type | Text |
| Resource Type | Article |
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