NDLI: Creating Defect Tolerance in Microfluidic Capacitive/Photonic Biosensors

Content Provider	IEEE Xplore Digital Library
Author	Chapman, G.H. Gray, B.L. Jain, V.K.
Copyright Year	2011
Abstract	Many biomedical sensors combine micro fluidic, electronic capacitive, and/or photonic capabilities. Micro fluidic sensors involve sealed channels through which the sample fluid containing biomedical materials flows with capacitive or photonic sensors detecting parameters contained in the liquid. However micro fluidic devices are prone to faults occurring when foreign particles in the bioliquid, or fluid bubbles, get lodged in the paths blocking a channel, thereby changing the fluidic flow in the device and affecting the parameters to be sensed. Thus, these systems require defect tolerant design in the micro fluidic and knowledge of how these changes will affect the parameters being sensed. To achieve fault tolerance we investigate a Cathedral Chamber design, with pillars supporting the roof at regular intervals. This prevents single blockages from stopping fluid flow through the system in a channel, as there are many paths. We discuss the potential causes and effects of such blockages. Monte Carlo analysis and simulations based on both randomly placed blockages and blockages occurring in low flow areas show that the Cathedral Chamber design significantly increases lifetime of the system, an average of 6 times more particles are required before full blockage occurs compared to an array of parallel channels. Fluid flow modeling shows parallel channels show rapid rise of pressure with the number of blockages while the Cathedral chamber shows much slower rise, which reaches a plateau pressure until it is blocked. The impact of these defects on the sensed parameters, such as capacitive measurement of the fluid or photonic measurements, is discussed.
Starting Page	181
Ending Page	189
File Size	1144169
Page Count	9
File Format	PDF
ISBN	9781457717130
ISSN	15505774
DOI	10.1109/DFT.2011.33
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-10-03
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microfluidics Fluids Fabrication Biosensors Capacitive sensors Fault tolerance defect avoidance Fault tolerant microfluidics Capacitive Biosensors encapsulated microfluidic chamber photonics sensors microfluidic blockage
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Unified high-level synthesis and module placement for defect-tolerant microfluidic biochips

Fault-tolerant architecture and CAD algorithm for field-programmable pin-constrained digital microfluidic biochips

The design and fabrication of microfluidic flow sensors

Microfluidic Packaging Integration with Electronic-Photonic Biosensors Using 3D Printed Transfer Molding

EECS 578 Project Check Point 4 Design of Fault-Tolerant Fault Tolerant Digital Microfluidics--based

A droplet routing technique for fault-tolerant digital microfluidic devices

Microfluidic biosensor using liquid crystal

Cost estimation of nanoscale partial defect tolerant arrays

Integration of three dimensional photonic crystals for refractive index sensing in microfluidics

Creating Defect Tolerance in Microfluidic Capacitive/Photonic Biosensors

Similar Documents

Unified high-level synthesis and module placement for defect-tolerant microfluidic biochips

Fault-tolerant architecture and CAD algorithm for field-programmable pin-constrained digital microfluidic biochips

The design and fabrication of microfluidic flow sensors

Microfluidic Packaging Integration with Electronic-Photonic Biosensors Using 3D Printed Transfer Molding

EECS 578 Project Check Point 4 Design of Fault-Tolerant Fault Tolerant Digital Microfluidics--based

A droplet routing technique for fault-tolerant digital microfluidic devices

Microfluidic biosensor using liquid crystal

Cost estimation of nanoscale partial defect tolerant arrays

Integration of three dimensional photonic crystals for refractive index sensing in microfluidics

Creating Defect Tolerance in Microfluidic Capacitive/Photonic Biosensors