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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Plyasunov, Sergey Arkin, Adam P. |
| Copyright Year | 2002 |
| Description | Author affiliation: Departments of Bioengineering and Chemistry, Howard Hughes Medical Institute, University of California, Physical Biosciences Division, E.O. Lawrence Berkeley National Laboratory, 1 Cyclotron Road MS 3-144, 94720, USA (Arkin, Adam P.) || Department of Physics, Howard Hughes Medical Institute, University of California, Physical Biosciences Division, E.O. Lawrence Berkeley National Laboratory, 1 Cyclotron Road MS 3-144, 94720, USA (Plyasunov, Sergey) |
| Abstract | Bacterial and animal cells are dynamic machines whose internal chemical networks perform hundreds of complex control and signal processing tasks to govern cellular development over time and in response to deterministic and stochastic signals from the environment. A central challenge in post-genomic biology is to discover the complete physical nature of these networks and to determine if there are principles of control and signal processing by which these cell operate and evolve. If such principles exist then they are handles by which cellular engineers can determine the best placement of external signals (such as pharmaceuticals) to cause a cell to move from an undesired state to a desired state. Here, initial attempts at determining the principles of control, the possible modular structure and the nature of signal flow in cellular networks are briefly introduced. |
| File Size | 709573 |
| File Format | |
| ISBN | 0780374029 |
| ISSN | 15206149 |
| DOI | 10.1109/ICASSP.2002.5745542 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2002-05-13 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Isotopes Impedance Pathogens Reliability theory |
| Content Type | Text |
| Resource Type | Article |
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