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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Linder, M. Duplaa, C. Couffinhal, T. Malandain, G. |
| Copyright Year | 2015 |
| Description | Author affiliation: Morpheme Team, INRIA, Sophia Antipolis, France (Linder, M.; Malandain, G.) || Adaptation Cardiovasculaire a l'Ischemie, INSERM, Pessac, France (Duplaa, C.; Couffinhal, T.) |
| Abstract | Angiogenesis is a key component of ontogenesis, but also of tumor development or in some pathology repair (i.e. ischemia). Deciphering the underlying mechanisms of vessel formation is of importance. We aimed at identifying and characterizing the genetic components that are involved in this development. This requires to compare the effect of each gene with respect to the others, hence appeals for quantitative comparisons. To that end, we propose then in this paper a methodology that first transforms a vascular image into a tree and second quantitatively analyze 3D vascular trees. Our preliminary experiments are conducted with images of the renal arterial network of different mutant mice. A first set of quantitative measurements are proposed that allow for group study. |
| Starting Page | 516 |
| Ending Page | 519 |
| File Size | 2085888 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781479923748 |
| DOI | 10.1109/ISBI.2015.7163924 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2015-04-16 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Mice Junctions Skeleton Three-dimensional displays Image reconstruction Image segmentation Cavity resonators quantitative biology micro-CT vascular imaging |
| Content Type | Text |
| Resource Type | Article |
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