NDLI: Blind depth-variant blur removal in confocal microscopy

Content Provider	IEEE Xplore Digital Library
Author	Ben Hadj, S. Blanc-Feraud, L. Aubert, G. Engler, G. Maalouf, E. Colicchio, B. Dieterlen, A.
Copyright Year	2013
Description	Author affiliation: Morpheme Res. Group, UNSA, Sophia Antipolis, France (Ben Hadj, S.; Blanc-Feraud, L.) \|\| Lab. MIPS-Lab..EL, Univ. of Haute-Alsace, Mulhouse, France (Maalouf, E.; Colicchio, B.; Dieterlen, A.) \|\| IBSV Unit, INRA, Sophia Antipolis, France (Engler, G.) \|\| Lab. J.A Dieudonne, UNSA, Nice, France (Aubert, G.)
Abstract	We are interested in blind restoration of 3D confocal microscopy images. One challenging problem in this system is the depth-variant (DV) blur due to refractive index mismatch. In our work, we simplify the problem by approximating the DV point spread function (PSF) by a convex combination of a set of space-invariant (SI) PSFs. We show that each SI PSF can be approximated by a Gaussian function given by few parameters. One advantage of such an approximation is that positivity and normalization of the PSF are naturally ensured. The problem is thus reduced to the estimation of the object and the PSF parameters. We design a new criterion allowing both estimations of the object and the DV PSF, with physical constraints included. The method is validated on simulated and real confocal microscopy data.
Sponsorship	IEEE
Starting Page	165
Ending Page	168
File Size	532072
Page Count	4
File Format	PDF
ISBN	9781467364560
ISSN	19457928
e-ISBN	9781467364553
DOI	10.1109/ISBI.2013.6556438
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-04-07
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microscopy Image restoration Silicon Estimation Approximation methods Optical microscopy Brain modeling regularization Blind restoration confocal microscopy depth-variant PSF JMAP
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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