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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Feng Shi Pew-Thian Yap Yong Fan Gilmore, J.H. Weili Lin Dinggang Shen |
| Copyright Year | 2010 |
| Description | Author affiliation: MRI Lab, Department of Radiology and BRIC, University of North Carolina at Chapel Hill, USA (Weili Lin) || IDEA Lab, Department of Radiology and BRIC, University of North Carolina at Chapel Hill, USA (Feng Shi; Pew-Thian Yap; Yong Fan; Dinggang Shen) || Department of Psychiatry, University of North Carolina at Chapel Hill, USA (Gilmore, J.H.) |
| Abstract | Neonatal brain MRI segmentation is challenging due to the poor image quality. Existing population atlases used for guiding segmentation are usually constructed by averaging all images in a population with no preference. However, such approaches diminish the important local inter-subject structural variability. In this paper, we propose a multi-region-multi-reference strategy for atlas building from a population. In brief, the brain is first parcellated into multiple anatomical regions, and for each region, the population images are classified into different sub-populations. The exemplars in sub-populations serve as structural references when determining the most suitable regional atlas for a to-be-segmented image. A final atlas is generated by combining all selected regional atlases, and a joint registration-segmentation strategy is employed for tissue segmentation. Experimental results demonstrate that segmentation with our atlas achieves high average tissue overlap rates with manual golden standard of 0.86 (SD 0.02) for gray matter (GM) and 0.83 (SD 0.03) for white matter (WM), and outperforms other atlases in comparison. |
| Starting Page | 964 |
| Ending Page | 967 |
| File Size | 452646 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424441259 |
| ISSN | 19457928 |
| DOI | 10.1109/ISBI.2010.5490148 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2010-04-14 |
| Publisher Place | Netherlands |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Pediatrics Magnetic resonance imaging Image segmentation Brain Buildings Radiology Psychiatry Fuses Voting Computational efficiency neonatal imaging Tissue segmentation multiple atlases joint registration-segmentation |
| Content Type | Text |
| Resource Type | Article |
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