NDLI: Effect of tissue factor on plasma and packed RBC clotting parameters

Content Provider	IEEE Xplore Digital Library
Author	Patel, D.R. Davidson, J. Kristol, D. Spillert, C.R.
Copyright Year	2004
Description	Author affiliation: New Jersey Inst. of Technol., Newark, NJ, USA (Patel, D.R.; Davidson, J.; Kristol, D.; Spillert, C.R.)
Abstract	Tissue factor (TF) is a transmembrane glycoprotein and the main triggering element for blood coagulation. Expression of TF on the cell surfaces and its appearance as a soluble molecule are characteristic features of acute and chronic inflammation in conditions such as arteriosclerosis leading to stroke and myocardial infection. A study was performed on human citrated whole blood, by separating plasma from the red blood cells. Ten microlitres of 25% tissue factor (TF) was added to both the plasma and packed red blood cells (RBC's), and the clotting time, rate of clot formation and the maximum strength of the clot determined. TF bearing samples clotted more rapidly and had greater clot strength when compared to that of control aliquots.
Sponsorship	BEACON Tyco Healthcare Reebok BEI The Whitaker Found
Starting Page	251
Ending Page	252
File Size	133226
Page Count	2
File Format	PDF
ISBN	0780382854
DOI	10.1109/NEBC.2004.1300089
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-04-17
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Coagulation Red blood cells Testing Viscosity Cloning Plasma properties Plasma materials processing Plasma displays Myocardium Humans
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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