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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Blanc, O. Virag, N. Vesin, J.-M. Kappenberger, L. |
| Copyright Year | 1964 |
| Abstract | Atrial fibrillation is the most frequent arrhythmia, provoking discomfort, heart failure and arterial embolisms. The aim of this work is to develop a simplified anatomical computer model of human atria for the study of atrial arrhythmias and the understanding of electrical propagation mechanisms. With the model the authors propose, up to 40 s of real-time propagation have been simulated on a single-processor computer. The size and the electrophysiological properties of the simulated atria are within realistic values and information about anatomy has been taken into account in a three-dimensional structure. Besides normal sinus beat, pathological phenomena such as flutter and fibrillation have been induced using a programmed stimulation protocol. One important observation in the authors' model is that atrial arrhythmias are a combination of functional and anatomical reentries and that the geometry plays an important role. This virtual atrium can reproduce electrophysiological observations made in humans but with the advantage of showing in great detail how arrhythmias are initiated and sustained. Such details are difficult or impossible to study in humans. This model will serve one as a tool to evaluate the impact of new therapeutic strategies and to improve them. |
| Sponsorship | IEEE Engineering in Medicine and Biology Society |
| Page Count | 9 |
| File Size | 196258 |
| Starting Page | 1229 |
| Ending Page | 1237 |
| File Format | |
| ISSN | 00189294 |
| Volume Number | 48 |
| Issue Number | 11 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2001-11-01 |
| Publisher Place | U.S.A. |
| Access Restriction | One Nation One Subscription (ONOS) |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Humans Computational modeling Atrial fibrillation Heart Computer simulation Anatomy Pathology Protocols Solid modeling Geometry |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biomedical Engineering |
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