NDLI: Axial control of thermal coagulation using a multi-element interstitial ultrasound applicator with internal cooling

Content Provider	IEEE Xplore Digital Library
Author	Deardorff, D.L. Diederich, C.J.
Copyright Year	1986
Abstract	A multi-element, direct-coupled ultrasound (US) applicator with internal water cooling was investigated for axial control of interstitial thermal coagulation. A prototype implantable applicator was constructed with a linear array of three tubular PZT ultrasound transducers (each 2.5 mm OD, 10 mm length, 360/spl deg/ emittance). Acoustic beam distributions from each element were measured and found to be collimated within the transducer length. The internally cooled applicator could sustain high levels of applied power to each transducer (0 to 40 W) and maintain acceptable applicator surface temperatures (<100/spl deg/C). Thermal performance of the applicator was investigated through heating trials in vivo (porcine thigh muscle and liver) and in vitro (bovine liver). The radial depth of thermal lesions produced was dependent on the applied power and sonication time and was controlled independently with power levels to each transducer element. With 18 W per element (applied electrical power) for 3 min, cylindrical thermal lesions were produced with a diameter of /spl sim/3 cm and a length ranging from 1.2 cm (with one element) to 3.5 cm (three elements). Higher powers (24 to 30 W) for 3 to 5 min provided increased depths of coagulation (/spl sim/4 cm diameter lesions). Analysis of axial lesion shapes demonstrated that individual variation of power to each transducer element provided control of axial heating and depth of coagulation (for custom lesion shapes); lesion lengths corresponded to the number of active transducers. This ability to control the heating distribution dynamically along the length of the applicator has potential for improved target localization of thermal coagulation and necrosis in high temperature thermal therapy.
Page Count	9
File Size	1215273
Starting Page	170
Ending Page	178
File Format	PDF
ISSN	08853010
Volume Number	47
Issue Number	1
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2000-01-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Coagulation Applicators Lesions Temperature control Acoustic transducers Ultrasonic transducers Heating Shape control Ultrasonic imaging Liver
Content Type	Text
Resource Type	Article
Subject	Acoustics and Ultrasonics Instrumentation Electrical and Electronic Engineering

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