NDLI: A Multi-Contrast, Multi-Resolution Phantom for Radionuclide Imaging Using a Single Activity Concentration Fill

Content Provider	IEEE Xplore Digital Library
Author	Wollenweber, S.D.
Copyright Year	1963
Abstract	The goal of the work is to design and prototype radionuclide phantom inserts constructed using a machinable porous material of water-like attenuation. The porous material enables multiple activity concentration `contrasts' while using a single concentration phantom fill. Further, features of multiple sizes are present within each of the contrasts. Available resolution phantoms for radionuclide imaging only allow for a single high-contrast measurement (1:0) and do not mimic typical patient imaging conditions that include a background activity. A hot rod phantom pattern was made using two porous materials and imaged alongside a non-porous equivalent inside a uniform cylinder. The phantom with inserts was imaged using [18F]-FDG on a PET/CT system. Using geometrically-defined image masks, mean values for the hot rod features and between-rod spaces were derived and the contrast recovery ratios compared for the non-porous and porous inserts. One of the prototype materials (EXP-1826) demonstrated reduced feature contrast ( ~ 40%) between the rods and the background. This material, with hydrophilic treatment, became fully saturated during phantom filling-simplifying the imaging process. Measurements of the rod contrast recovery in the various phantom sections demonstrated the phantom's utility for comparing and potentially optimizing image reconstruction parameter settings under varying imaging conditions at reduced contrast.
Sponsorship	IEEE Nuclear and Plasma Sciences Society Computer Applications in Nuclear and Plasma Sciences (CANPS) Lawrence Berkeley Lab. Lawrence Livermore Nat. Lab. APS College of William and Mary Continuous Electron Beam Accelerator Facility NASA Defence Nuclear Agency Sandia National Laboratories Jet Propulsion Laboratory Brookhaven Nat. Lab. Lawrence Livermore Nat. Lab IEEE/NPPS Radiat. Effects Committee Defence Nuclear Agency/DoD Sandia National Laboratories/DOE Jet Propulsion Laboratory/NASA Phillips Lab./DoD
Starting Page	2503
Ending Page	2509
Page Count	7
File Size	2028035
File Format	PDF
ISSN	00189499
Volume Number	61
Issue Number	5
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2014-01-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Materials Positron emission tomography Imaging phantoms Computed tomography Phantoms Image reconstruction phantoms Data analysis image analysis positron emission tomography
Content Type	Text
Resource Type	Article
Subject	Nuclear and High Energy Physics Electrical and Electronic Engineering Nuclear Energy and Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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