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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | de Almeida, T.M. Piedade, M.S. Sousa, L.A. Germano, J. Lopes, P.A.C. Cardoso, F.A. Freitas, P.P. |
| Copyright Year | 1963 |
| Abstract | A fully integrated biochip based on a 16 × 16 scalable matrix structure of aluminum oxide magnetic tunnel junctions (MTJs) and thin-film diodes (TFDs of hydrogenated amorphous silicon) was fabricated and included as the biosensor of a portable handheld microsystem developed for biomolecular recognition detection using magnetic labels [deoxyribonucleic acid (DNA) hybridization, antibody antigen interaction, etc.]. The system uses magnetic field arraying of magnetically tagged biomolecules and can potentially be used to detect single or few biomolecules. Each biosensor matrix node is the series between a TFD (p-i-n or Schottky-barrier type) and an MTJ. In this paper, this matrix basic cell biosensor element is completely characterized and modeled. Experimental measured data are provided and compared with the proposed theoretical models results. It is shown that the diode may be used both as the matrix switching device and as an in-site temperature sensor and that the MTJ may act as the magnetoresistive sensor for detecting the fringe field of immobilized magnetic markers. Therefore, the fabricated fully integrated biochip included in the developed handheld microsystem may be used for biomolecular recognition. |
| Sponsorship | IEEE Instrumentation and Measurement Society Bureau international des poids et mesures IEEE International Bureau of Weights and Measures (BIPM) URSI NBS Agency Ind. Sci. & Technol., Min. Int. Trade & Ind. Sci. Council Japan International Union of Pure and Applied Physics (IUPAP) NIST NRCC National Conference of Standards Laboratories (NCSL) Allen Osborne Associates Andeen-Hagerling, Inc. Ballantine Lab. Inc. Clarke-Hess Communications Research Corp. Fluke Corporation Guildline Instruments Hewlett-Packard Co. Julie Res. Lab. Inc. Keithley Instruments, Inc. Measurements International Ltd. Canada QuadTech Inc. Quantum Design Inc. Rotek Instrum. Corp. Tegam Inc. Tektronix Inc |
| Starting Page | 92 |
| Ending Page | 100 |
| Page Count | 9 |
| File Size | 890422 |
| File Format | |
| ISSN | 00189456 |
| Volume Number | 59 |
| Issue Number | 1 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2010-01-01 |
| Publisher Place | U.S.A. |
| Access Restriction | One Nation One Subscription (ONOS) |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Tunneling magnetoresistance Biosensors Magnetic tunneling Amorphous magnetic materials Schottky diodes P-i-n diodes Magnetic field measurement Molecular biophysics Temperature sensors Aluminum oxide system modeling Biomedical transducers magnetoresistive devices p-i-n diodes |
| Content Type | Text |
| Resource Type | Article |
| Subject | Instrumentation Electrical and Electronic Engineering |
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