NDLI: <emphasis emphasistype=italic>In Vivo</emphasis> High-ResolutionConductivity Imaging of the Human Leg Using MREIT: The First Human Experiment

Content Provider	IEEE Xplore Digital Library
Author	Hyung Joong Kim Young Tae Kim Minhas, A.S. Woo Chul Jeong Eung Je Woo Jin Keun Seo Kwon, O.J.
Copyright Year	1982
Abstract	We present the first in vivo cross-sectional conductivity image of the human leg with 1.7 mm pixel size using the magnetic resonance electrical impedance tomography (MREIT) technique. After a review of its experimental protocol by an Institutional Review Board (IRB), we performed MREIT imaging experiments of four human subjects using a 3 T MRI scanner. Adopting thin and flexible carbon-hydrogel electrodes with a large surface area and good contact, we could inject as much as 9 mA current in a form of 15 ms pulse into the leg without producing a painful sensation and motion artifact. Sequentially injecting two imaging currents in two different directions, we collected induced magnetic flux density data inside the leg. Scaled conductivity images reconstructed by using the single-step harmonic B _z algorithm well distinguished different parts of the subcutaneous adipose tissue, muscle, crural fascia, intermuscular septum and bone inside the leg. We could observe spurious noise spikes in the outer layer of the bone primarily due to the MR signal void phenomenon there. Around the fat, the chemical shift of about two pixels occurred obscuring the boundary of the fat region. Future work should include a fat correction method incorporated in the MREIT pulse sequence and improvements in radio-frequency coils and image reconstruction algorithms. Further human imaging experiments are planned and being conducted to produce conductivity images from different parts of the human body.
Sponsorship	IEEE Engineering in Medicine and Biology Society IEEE Nuclear and Plasma Sciences Society IEEE Signal Processing Society IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society
Page Count	7
File Size	1978138
Starting Page	1681
Ending Page	1687
File Format	PDF
ISSN	02780062
Volume Number	28
Issue Number	11
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-11-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	In vivo Humans Leg Conductivity Magnetic resonance imaging Image reconstruction Bones Pixel Magnetic resonance Surface impedance magnetic resonance electrical impedance tomography (MREIT) Conductivity image in vivo human imaging
Content Type	Text
Resource Type	Article
Subject	Electrical and Electronic Engineering Computer Science Applications Radiological and Ultrasound Technology Software

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