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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Prout, D.L. Silverman, R.W. Chatziioannou, A. |
| Copyright Year | 1963 |
| Abstract | The design of an imaging system capable of detecting both high-energy /spl gamma/-rays and optical wavelength photons is underway at the Crump Institute for Molecular Imaging. This system will noninvasively image small animal models in vivo for the presence of positron emission tomographic (PET) and optical signals. The detector will consist of modules of multichannel photomultiplier tubes (MC-PMT) coupled to arrays of scintillator crystals. The MC-PMT will detect both the photons produced due to bioluminescence and the photons generated by the interaction of /spl gamma/-rays within the crystals. The long wavelength photons produced through bioluminescence are only slightly attenuated by these crystals and are detected directly at the photocathode of the MC-PMT, resulting in signals of small (5-10 mV) short (/spl sim/15 ns) pulses. In contrast, annihilation (511 keV) /spl gamma/-rays interacting in the scintillator crystal send large bursts of photons to the PMT, and result in pulses that can be as large as 500 mV and > 200 ns duration. The processing of pulses with such different characteristics in a single circuit requires significant alteration of the standard pulse processing circuitry used in PET scanners. In this paper, we discuss the requirements of such a circuit and show the results of implementation of one design using single and multiple channel PMTs. |
| Sponsorship | IEEE Nuclear and Plasma Sciences Society Computer Applications in Nuclear and Plasma Sciences (CANPS) Lawrence Berkeley Lab. Lawrence Livermore Nat. Lab. APS College of William and Mary Continuous Electron Beam Accelerator Facility NASA Defence Nuclear Agency Sandia National Laboratories Jet Propulsion Laboratory Brookhaven Nat. Lab. Lawrence Livermore Nat. Lab IEEE/NPPS Radiat. Effects Committee Defence Nuclear Agency/DoD Sandia National Laboratories/DOE Jet Propulsion Laboratory/NASA Phillips Lab./DoD |
| Starting Page | 28 |
| Ending Page | 32 |
| Page Count | 5 |
| File Size | 342474 |
| File Format | |
| ISSN | 00189499 |
| Volume Number | 52 |
| Issue Number | 1 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2005-02-01 |
| Publisher Place | U.S.A. |
| Access Restriction | One Nation One Subscription (ONOS) |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Positron emission tomography Optical detectors Photonic crystals Biomedical optical imaging Stimulated emission Optical attenuators Circuits Gamma ray detection Gamma ray detectors Bioluminescence small animal imaging positron emission tomography (PRT) signal processing |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nuclear and High Energy Physics Electrical and Electronic Engineering Nuclear Energy and Engineering |
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