NDLI: Signal processing techniques in genomic engineering

Content Provider	IEEE Xplore Digital Library
Author	Xin-Yun Zhang Fei Chen Yuan-Ting Zhang Agner, S.C. Akay, M. Zu-Hong Lu Waye, M.M.Y. Tsui, S.K.-W.
Copyright Year	1963
Abstract	Now that the human genome has been sequenced, the measurement, processing, and analysis of specific genomic information in real time are gaining considerable interest because of their importance to better the understanding of the inherent genomic function, the early diagnosis of disease, and the discovery of new drugs. Traditional methods to process and analyze deoxyribonucleic acid (DNA) or ribonucleic acid data, based on the statistical or Fourier theories, are not robust enough and are time-consuming, and thus not well suited for future routine and rapid medical applications, particularly for emergency cases. In this paper, we present an overview of some recent applications of signal processing techniques for DNA structure prediction, detection, feature extraction, and classification of differentially expressed genes. Our emphasis is placed on the application of wavelet transform in DNA sequence analysis and on cellular neural networks in microarray image analysis, which can have a potentially large effect on the real-time realization of DNA analysis. Finally, some interesting areas for possible future research are summarized, which include a biomodel-based signal processing technique for genomic feature extraction and hybrid multidimensional approaches to process the dynamic genomic information in real time.
Sponsorship	IEEE Publication
Starting Page	1822
Ending Page	1833
Page Count	12
File Size	620457
File Format	PDF
ISSN	00189219
Volume Number	90
Issue Number	12
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-12-01
Publisher Place	U.S.A.
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Signal processing Genomics Bioinformatics Multidimensional signal processing DNA Biomedical signal processing Image sequence analysis Feature extraction Image analysis Humans
Content Type	Text
Resource Type	Article
Subject	Computer Science Electrical and Electronic Engineering

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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