NDLI: Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes

Content Provider	IEEE Xplore Digital Library
Author	Tenney, C.R. Tornai, M.P. Smith, M.F. Turkington, T.G. Jaszczak, R.J.
Copyright Year	1963
Abstract	Depleted uranium (DU) pinhole collimators are evaluated for small-volume SPECT imaging of 511-keV gammas, with a view toward small-animal imaging. Tungsten (W) pinholes are examined for comparison. Line source measurements show planar full-width at half-maximum (FWHM) as low as 6.5 mm for a 1-mm DU pinhole, with SPECT system FWHM of 5.0 mm at 43-mm ROR and 6.7 mm at 69-mm ROR. Planar FWHM is smaller for DU than for W pinholes but is insensitive to aperture size for pinholes of 1-3 mm diameter at this energy for the collimators studied. These trends indicate penetration at pinhole edges, as confirmed by LSF shape and full-width at tenth-maximum trends. In SPECT scans of rod phantoms at 71-mm ROR, DU pinholes were only barely able to resolve cold rods as large as 4.7 mm (center-to-center spacing=2/spl times/diameter). For both F-18 alone and F-18 imaged along with Tc-99m, 3.9-mm hot rods were resolved. Tc-99m scans resolved 2.3- mm rods with F-18 present and 1.5-mm rods without F-18. DU pinhole SPECT at 511 keV does not currently match the spatial resolution of high-resolution positron emission tomography (PET) but is open to improvement and, unlike PET, is capable of simultaneous multiple-isotope acquisitions.
Sponsorship	IEEE Nuclear and Plasma Sciences Society Computer Applications in Nuclear and Plasma Sciences (CANPS) Lawrence Berkeley Lab. Lawrence Livermore Nat. Lab. APS College of William and Mary Continuous Electron Beam Accelerator Facility NASA Defence Nuclear Agency Sandia National Laboratories Jet Propulsion Laboratory Brookhaven Nat. Lab. Lawrence Livermore Nat. Lab IEEE/NPPS Radiat. Effects Committee Defence Nuclear Agency/DoD Sandia National Laboratories/DOE Jet Propulsion Laboratory/NASA Phillips Lab./DoD
Starting Page	1483
Ending Page	1489
Page Count	7
File Size	136002
File Format	PDF
ISSN	00189499
Volume Number	48
Issue Number	4
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2001-08-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Optical collimators Single photon emission computed tomography Spatial resolution Optical imaging Positron emission tomography Tungsten Apertures Shape Imaging phantoms Energy resolution
Content Type	Text
Resource Type	Article
Subject	Nuclear and High Energy Physics Electrical and Electronic Engineering Nuclear Energy and Engineering

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