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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Van Leemput, K. Maes, F. Vandermeulen, D. Suetens, P. |
| Copyright Year | 1982 |
| Abstract | The authors propose a model-based method for fully automated bias field correction of MR brain images. The MR signal is modeled as a realization of a random process with a parametric probability distribution that is corrupted by a smooth polynomial inhomogeneity or bias field. The method the authors propose applies an iterative expectation-maximization (EM) strategy that interleaves pixel classification with estimation of class distribution and bias field parameters, improving the likelihood of the model parameters at each iteration. The algorithm, which can handle multichannel data and slice-by-slice constant intensity offsets, is initialized with information from a digital brain atlas about the a priori expected location of tissue classes. This allows full automation of the method without need for user interaction, yielding more objective and reproducible results. The authors have validated the bias correction algorithm on simulated data and they illustrate its performance on various MR images with important field inhomogeneities. They also relate the proposed algorithm to other bias correction algorithms. |
| Sponsorship | IEEE Engineering in Medicine and Biology Society IEEE Nuclear and Plasma Sciences Society IEEE Signal Processing Society IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society |
| Page Count | 12 |
| File Size | 1102902 |
| Starting Page | 885 |
| Ending Page | 896 |
| File Format | |
| ISSN | 02780062 |
| Volume Number | 18 |
| Issue Number | 10 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 1999-10-01 |
| Publisher Place | U.S.A. |
| Access Restriction | One Nation One Subscription (ONOS) |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Brain modeling Image segmentation Biomedical imaging Signal processing Random processes Probability distribution Polynomials Iterative methods Iterative algorithms Automation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Electrical and Electronic Engineering Computer Science Applications Radiological and Ultrasound Technology Software |
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