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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Koch, C.M. Winfrey, A.L. |
| Copyright Year | 1965 |
| Abstract | General principles are developed using a finite element model regarding how time-dependent power dissipation of magnetic nanoparticles can be used to optimize hyperthermia selectivity. To make the simulation more realistic, the finite size and spatial location of each individual nanoparticle is taken into consideration. When energy input into the system and duration of treatment is held constant, increasing the maximum power dissipation of nanoparticles increases concentrations of energy in the tumor. Furthermore, when the power dissipation of magnetic nanoparticles rises linearly, the temperature gradient on the edge of the tumor increases exponentially. With energy input held constant, the location and duration of maximum power dissipation in the treatment time scheme will affect the final energy concentration inside the tumor. Finally, connections are made between the simulation results and optimization of the design of nanoparticle power dissipation time-schemes for hyperthermia. |
| Sponsorship | IEEE Magnetics Society |
| Starting Page | 1 |
| Ending Page | 7 |
| Page Count | 7 |
| File Size | 1071280 |
| File Format | |
| ISSN | 00189464 |
| Volume Number | 50 |
| Issue Number | 10 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2014-01-01 |
| Publisher Place | U.S.A. |
| Access Restriction | One Nation One Subscription (ONOS) |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Hyperthermia Power dissipation Tumors Heating Finite element analysis Nanoparticles Mathematical model treatment planning Hyperthermia optimization finite-element modeling magnetic nanoparticles |
| Content Type | Text |
| Resource Type | Article |
| Subject | Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering |
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