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Mineralized three-dimensional bone constructs
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Copyright Year | 2013 |
| Description | The present disclosure provides ex vivo-derived mineralized three-dimensional bone constructs. The bone constructs are obtained by culturing osteoblasts and osteoclast precursors under randomized gravity vector conditions. Preferably, the randomized gravity vector conditions are obtained using a low shear stress rotating bioreactor, such as a High Aspect Ratio Vessel (HARV) culture system. The bone constructs of the disclosure have utility in physiological studies of bone formation and bone function, in drug discovery, and in orthopedics. |
| File Size | 2141872 |
| Page Count | 15 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_20150003126 |
| Archival Resource Key | ark:/13960/t9f52p12g |
| Language | English |
| Publisher Date | 2013-10-15 |
| Access Restriction | Open |
| Subject Keyword | Aerospace Medicine Bone Mineral Content Patents Osteocalcin Gravitation Tissue Engineering Bioreactors Imaging Techniques Bones Tissue Culturing Osteoblasts Osteogenesis Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Patent |
