NDLI: Plasma cytokine levels during long-duration spaceflight

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Plasma cytokine levels during long-duration spaceflight

Content Provider	NASA Technical Reports Server (NTRS)
Author	Crucian, Brian E. Zwart, Sara R. Smith, Scott M. Quiriarte, Heather A. Sams, Clarence F.
Copyright Year	2012
Description	Determine the in-flight status of immunity, physiological stress, viral immunity/reactivation. Specific measurements include leukocyte distribution, T cell function, cytokine production profiles (mRNA, intracellular, secreted, plasma), virus-specific T cell number/function, latent herpesvirus reactivation, stress hormone levels. Determine the clinical risk related to immune dysregulation for exploration class spaceflight, as well as an appropriate monitoring strategy for spaceflight-associated immune dysfunction, that could be used for the evaluation of countermeasures. Specific Study Objectives: Determine the nutritional status of astronauts before, during, and after spaceflight ensure adequate intake of energy, protein, and vitamins during missions. The Clinical Nutritional Status Assessment measures dietary intake, body composition, protein, bone, iron, mineral, vitamin, and antioxidant status (60 total analytes). Currently, it is a medical requirement for U.S. crewmembers on-board the ISS. The results of data analysis are used both to understand the connections between nutrition and human health during space flight, and to develop effective dietary strategies to reduce adverse health impacts (including bone loss, loss of important vitamins and minerals, and increased genetic damage from radiation).
File Size	1380277
Page Count	17
File Format	PDF
Alternate Webpage(s)	http://archive.org/details/NASA_NTRS_Archive_20120007587
Archival Resource Key	ark:/13960/t75t8mw2n
Language	English
Publisher Date	2012-02-14
Access Restriction	Open
Subject Keyword	Aerospace Medicine Immune Systems Antigens Immunology Nutrition Cytology Physiological Defenses Astronauts Physiology Leukocytes Long Duration Space Flight Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science
Content Type	Text
Resource Type	Presentation

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