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Mathematical modeling of the origins of life
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Author | Pohorille, Andrew |
| Copyright Year | 2006 |
| Description | The emergence of early metabolism - a network of catalyzed chemical reactions that supported self-maintenance, growth, reproduction and evolution of the ancestors of contemporary cells (protocells) was a critical, but still very poorly understood step on the path from inanimate to animate matter. Here, it is proposed and tested through mathematical modeling of biochemically plausible systems that the emergence of metabolism and its initial evolution towards higher complexity preceded the emergence of a genome. Even though the formation of protocellular metabolism was driven by non-genomic, highly stochastic processes the outcome was largely deterministic, strongly constrained by laws of chemistry. It is shown that such concepts as speciation and fitness to the environment, developed in the context of genomic evolution, also held in the absence of a genome. |
| File Size | 187419 |
| Page Count | 2 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_20060022562 |
| Archival Resource Key | ark:/13960/t9x112p43 |
| Language | English |
| Publisher Date | 2006-01-01 |
| Access Restriction | Open |
| Subject Keyword | Protobiology Biological Evolution Stochastic Processes Mathematical Models Chemical Evolution Metabolism Genome Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Article |
