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Use of injectable promethazine to decrease symptom scores of space motion sickness
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Author | Nicogossian, A. E. Beck, B. G. |
| Copyright Year | 1992 |
| Description | Space motion sickness (SMS) has been a problem affecting approximately 74 percent of first time shuttle flyers. Promethazine injections have been used for 29 cases of SMS to decrease the severity of their illness. Although reported to be effective in reducing symptoms in 27 of the 29 cases, there has been no proof of its efficacy. Methods: Retrospective analysis of medical debriefs examining the symptom scores for nausea, vomiting, decreased appetite, and stomach awareness were performed. Each symptom is rated on a mild = 1, moderate = 2, severe = 3 system for each flight day. Crewmember scores for the first three flight days on an initial flight in which injectable promethazine had not been used were compared to scores in a later flight in which the promethazine was utilized. Scores were also compared in a similar group of crewmembers who did not use promethazine. Results: There was a decrease in median scores for all symptoms except nausea, however, it was significant (p = 0.14) only for the vomiting scores. This significant decrease was not seen in the control group. Conclusions: Injectable promethazine has been associated with a significant decrease in vomiting compared to earlier flights in which injectable promethazine was not used. |
| File Size | 326145 |
| Page Count | 2 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_19950010326 |
| Archival Resource Key | ark:/13960/t2q57hn3d |
| Language | English |
| Publisher Date | 1992-05-14 |
| Access Restriction | Open |
| Subject Keyword | Aerospace Medicine Spacecrews Stomach Signs and Symptoms Gravitational Physiology Vomiting Promethazine Space Shuttles Motion Sickness Nausea Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Article |
