NDLI: Experimental studies of gastric dysfunction in motion sickness: the effect of gastric and vestibular stimulation on the vagal and splanchnic gastric efferents

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Experimental studies of gastric dysfunction in motion sickness: the effect of gastric and vestibular stimulation on the vagal and splanchnic gastric efferents

Content Provider	NASA Technical Reports Server (NTRS)
Author	Daunton, Nancy G. Jiang, Z. Y. Fox, Robert A. Niijima, A.
Copyright Year	1991
Description	The experiments were conducted in anaesthetized rats. In the first part of the experiments, the effect of CuSO4 on the afferent activity in the gastric branch of the vagus nerve was investigated. Gastric perfusion of CuSO4 solution (0.04 percent and 0.08 percent) provoked an increase in afferent activity. In the second part of the experiments, the reflex effects of gastric perfusion of CuSO4 solution, repetitive stimulation of the gastric vagus nerve, and caloric stimulation of the right vestibular apparatus (5-18 C water) on gastric autonomic outflow were investigated. The results of these experiments showed that these three different types of stimulation caused an inhibition in efferent activity of the gastric vagus nerve and a slight activation of the splanchnic gastric efferents. The summation of the effect of each stimulation was also observed. These results, therefore, provide evidence for a possible integrative inhibitory function of the vagal gastric center as well as an excitatory function of gastric sympathetic motoneurons in relation to motion sickness.
File Size	342685
Page Count	4
File Format	PDF
Alternate Webpage(s)	http://archive.org/details/NASA_NTRS_Archive_19940017438
Archival Resource Key	ark:/13960/t50g8k960
Language	English
Publisher Date	1991-01-01
Access Restriction	Open
Subject Keyword	Vestibules Vomiting Autonomic Nervous System Gastrointestinal System Nerves Motion Sickness Rats Stimulation Sulfates Copper Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science
Content Type	Text
Resource Type	Article

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