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Pharmacologic counter measures minimizing post-space flight orthostatic intolerance. [bed rest, drug disposition, and physiological function]
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Author | Harrison, D. C. Kates, R. |
| Copyright Year | 1982 |
| Description | The effect of bed rest on drug disposition and physiological function was investigated as part of a project to determine the cardiovascular effects of space flight. One group of subjects was given doses of lidocane, penicillin-G, and ICG during a control period and following seven days of bed rest. Cardiac function was evaluated by echo-cardiography. Renal function was evaluated in a second group before and after several days of bed rest. Inulin, para-aminohippurate, and dextran clearances were studied. In the first group, the post-bed rest parameters were not statistically different from the pre-bed rest valves. In the second study, renal function did not change significantly after seven days of bed rest. Plans for future research are reviewed. |
| File Size | 5599818 |
| Page Count | 15 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_19840023866 |
| Archival Resource Key | ark:/13960/t3qv8bx6x |
| Language | English |
| Publisher Date | 1982-03-01 |
| Access Restriction | Open |
| Subject Keyword | Aerospace Medicine Drugs Cardiovascular System Physiological Effects Echocardiography Renal Function Penicillin Space Flight Stress Project Planning Pharmacology Clinical Medicine Orthostatic Tolerance Bed Rest Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Technical Report |
