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Bed-rest studies: fluid and electrolyte responses
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Author | Greenleaf, J. E. |
| Copyright Year | 1983 |
| Description | Confinement in the horizontal position for 2 to 3 weeks results in a chronic decrease in plasma volume, increased interstitial fluid volume, and unchanged or slightly increased extracellular fluid volume. Concentrations of blood electrolytes, glucose, and nitrogenous constituents remain within normal limits of variability when maintenance levels of isometric or isotonic exercise are performed for 1 hr/day. Hematocrit and plasma osmolality can be elevated significantly throughout bed rest (BR). Significant diuresis occurs on the first day, and increases in urine Na and Ca continue throughout BR, although voluntary fluid intake is unchanged. Urine Na and K are evaluated during the second week of BR in spite of stabilization of PV and extracellular volume. The initial diuresis probably arises from the extracellular fluid while subsequent urine loss above control levels must come from the intracellular fluid. Preservation of the extracellular volume takes precedance over maintenance of the intracellular fluid volume. The functioning of a natriuretic factor (hormone) to account for the continued increased loss of Na in the urine is suggested. |
| File Size | 6141171 |
| Page Count | 17 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_19830015889 |
| Archival Resource Key | ark:/13960/t85j2c41n |
| Language | English |
| Publisher Date | 1983-04-01 |
| Access Restriction | Open |
| Subject Keyword | Aerospace Medicine Body Fluids Diuresis Sodium Hydrostatic Pressure Glucose Hormones Urination Bed Rest Electrolyte Metabolism Potassium Blood Plasma Ntrs Nasa Technical Reports ServerĀ (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Article |