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Validation of a model for investigating red cell mass changes during weightlessness
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Author | Leonard, J. I. |
| Copyright Year | 1976 |
| Description | The model, both the conceptual model and simulation model, provided a convenient framework on which to demonstrate the commonality between such diverse stresses as descent from altitude, red cell infusions, bed rest, and weightlessness. The results suggest that all of these stresses induce an increased blood hematocrit leading to tissue hyperoxia and eventual inhibition of the erythyocyte producing circuit until the hyperoxic condition is relieved. The erythropoietic system was acting, in these situations, as if it were an hematocrit sensor and regulator. In these terms the decreases in red cell mass during Skylab may be explained in terms of normal feedback regulation of the erythropoietic system in the face of sustained decreases in plasma colume. |
| File Size | 5493757 |
| Page Count | 29 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_19790016463 |
| Archival Resource Key | ark:/13960/t8sb8vx7f |
| Language | English |
| Publisher Date | 1976-05-10 |
| Access Restriction | Open |
| Subject Keyword | Aerospace Medicine Feedback Erythrocytes Hematocrit Skylab Program Models Weightlessness Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Article |
