NDLI: Biosensors for the Rapid Detection of Cardiovascular Biomarkers of Vital Interest: Needs, Analysis and Perspectives

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Biosensors for the Rapid Detection of Cardiovascular Biomarkers of Vital Interest: Needs, Analysis and Perspectives

Content Provider	Hyper Articles en Ligne (HAL)
Author	Abensur Vuillaume, Laure Frija-Masson, Justine Hadjiat, Meriem Riquier, Thomas D’ortho, Marie-Pia Le Borgne, Pierrick Goetz, Christophe Voss, Paul, L Ougazzaden, Abdallah Salvestrini, Jean-Paul Leïchlé, Thierry
Abstract	We have previously surveyed a panel of 508 physicians from around the world about which biomarkers would be relevant if obtained in a very short time frame, corresponding to emergency situations (life-threatening or not). The biomarkers that emerged from this study were markers of cardiovascular disease: troponin, D-dimers, and brain natriuretic peptide (BNP). Cardiovascular disease is a group of disorders affecting the heart and blood vessels. At the intersection of medicine, basic research and engineering, biosensors that address the need for rapid biological analysis could find a place of choice in the hospital or primary care ecosystem. Rapid, reliable, and inexpensive analysis with a multi-marker approach, including machine learning analysis for patient risk analysis, could meet the demand of medical teams. The objective of this opinion review, proposed by a multidisciplinary team of experts (physicians, biologists, market access experts, and engineers), is to present cases where a rapid biological response is indeed valuable, to provide a short overview of current biosensor technologies for cardiac biomarkers designed for a short result time, and to discuss existing market access issues.
Related Links	https://laas.hal.science/hal-04266801/file/JPM-CardiacMarkers-Abensur2022.pdf
ISSN	20754426
DOI	10.3390/jpm12121942
Journal	Journal of Personalized Medicine
Volume Number	12
Language	English
Publisher	HAL CCSD MDPI
Publisher Date	2022-11-22
Access Restriction	Open
Subject Keyword	D-dimers cardiac biomarkers biosensors cardiac biomarkers biosensors troponin BNP D-dimers troponin BNP Engineering Sciences [physics]
Content Type	Text
Resource Type	Article
Subject	Physics and Astronomy Medicine

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