Please wait, while we are loading the content...
| Content Provider | frontiers |
|---|---|
| Author | Wang, Cheng Yan, Junbin He, Beihui Zhang, Shuo Xu, Sumei |
| Abstract | Background: In China, the prevalence and mortality of colorectal cancer (CRC) have always been high, and more than 95% of CRC have evolved from colorectal polyps (CPs), especially adenoma. Early detection and treatment of CPs through colonoscopy is essential to reduce the incidence of CRC. Helicobacter pylori (Hp) is regarded as a risk factor for gastritis and gastric cancer and may also be a risk factor for CPs and CRC. However, few studies based on volume clinical cases existed in China to clarify whether Hp is a risk factor of CPs and CRC, whether Hp-positive patients need to advance the time of colonoscopy. The article attempts to make up for the deficiency. Method: The cross-sectional study was conducted based on 13,037 cases without the treatment history of Hp and who accepted the first gastroscopy and colonoscopy simultaneously in The First Affiliated Hospital of Zhejiang Chinese Medical University from January 2018 to December 2019. Pearson x2 test and logistic regression were used to determine whether Hp is a risk factor of CPs and CRC. Multi-factor analysis of variance was used to define the impact of Hp on the CPs prevalence with different ages, gender. Results: For Chinese, Hp is the risk factor of CPs and CRC. The odds ratio (OR) value is 1.228(95% CI, 1.130 to 1.336) and 1.862(95% CI 1.240-2.796), respectively. Hp-positive patients have a higher probability of multiple or large intestinal polyps. However, Hp infection does not increase the incidence of adenomas, nor does it affect the pathological type of adenomas. The OR of HP on the risk of CPs was 1.432(95%CI 1.275-1.608) for the males but increased to 1.937(95%CI 1.334-2.815) for aged 35 to 40. For females, the results were similar. Conclusions: For the Chinese, Hp is a risk factor for CPs and CRC(OR>1); The infection of Hp increased CPs risk in the Chinese of all ages, especially aged 35-40, suggesting Hp-positive patients should accept colonoscopy frequently. |
| ISSN | 2234943X |
| DOI | 10.3389/fonc.2021.698898 |
| Volume Number | 11 |
| Journal | Frontiers in Oncology |
| Language | English |
| Publisher Date | 2021-08-26 |
| Access Restriction | Open |
| Subject Keyword | Colorectal cancer (CRC) Adenoma Colorectal polyps (CPs) Cross-section study Age Chinese |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cancer Research Oncology |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|