Please wait, while we are loading the content...
| Content Provider | frontiers |
|---|---|
| Author | Soriano, Alessandra Soriano, Marco Oliva, Rocco Smith, Wendy M. |
| Abstract | and tolerance in the uvea. Both leukocyte and stromal biology in this peculiar microanatomical niche need to be further investigated, as it remains unclear how these two populations interact to permit the inflammatory 'burden', where required.For instance, the role of fibroblasts in the uvea remains unclear, differently from their role in other microenvironment such as the gut, where transcriptome analysis recently allowed to shed light on how many and various are the fibroblast populations among the crypt-villus axis. Similarly, in IBD single-cell profiling over colonic mesenchymal cells revealed four subsets of fibroblasts expressing divergent transcriptional regulators and functional pathways.Nowadays we know that niche population located in proximity to epithelial crypts fuels inflammation and barrier dysfunction (4). We also know that uveitis (together with episcleritis and scleritis) can be an extra-intestinal manifestation of IBD which may precede or follow systemic disease onset. Interestingly enough, in this particular case, we know that usually by treating the underlying IBD, ocular symptoms tend to improve accordingly. However, we still do not know why in other cases ocular manifestations (i.e. uveitis or scleritis) have a clinical course independently from the systemic disease course of IBD.As Reekie et al. extensively discussed, some open questions could be answered by integrating evidence coming from studies already performed on other systemic immune-mediated... |
| ISSN | 2296858X |
| DOI | 10.3389/fmed.2022.1033817 |
| Volume Number | 9 |
| Journal | Frontiers in Medicine |
| Language | English |
| Publisher Date | 2022-11-24 |
| Access Restriction | Open |
| Subject Keyword | Treatment Pathogenesis Epidemiology Uveitis Autoimmunity |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|