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| Content Provider | frontiers |
|---|---|
| Author | Nitzsche, Bianca Höpfner, Michael |
| Abstract | testicular cancer rather showing an increased prevalence and incidence in younger adults, most urologic cancers develop in the older male population. All types of urologic cancers represent a problem of major concern and some of them (e.g. prostate cancer) rank among the three most frequent cancers, worldwide and account for a large number of cancer related deaths per year (1). And even more alarming the incidence of urologic cancer is rising due to demographic reasons such as population growth and aging but also due to environmental factors, which have been linked to the development and growth of single urologic cancers, too (e.g. kidney, prostate, bladder) (2).In the past decade, the understanding of dysregulated pathways in urologic cancers as well as the identification of potential biomarkers helped to identify new targets and pathways for novel therapeutic approaches. In this respect new immunomodulatory substances, antiangiogenic agents, growth factor receptor inhibitors or the targeting of epigenetically modulated signaling pathways have become interesting and promising starting points for future medical treatment of urologic cancer.Besides being more effective, targeted approaches also aim at reducing the severe short-and longterm side effects known for conventional chemo-and radiotherapies.The idea of the special issue "Advances in molecular targeted therapies of urologic cancers" was to bring together experts in the field reporting on recent (pre-)clinical findin... |
| ISSN | 2234943X |
| DOI | 10.3389/fonc.2022.1062015 |
| Volume Number | 12 |
| Journal | Frontiers in Oncology |
| Language | English |
| Publisher Date | 2022-10-19 |
| Access Restriction | Open |
| Subject Keyword | Bladder cancer (BCa) Kidney cancer Molecular targeted theraphy Prostate cancer CircRNA |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cancer Research Oncology |
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